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Phosphorylation of the C-terminal tail of proteasome subunit α7 is required for binding of the proteasome quality control factor Ecm29

The proteasome degrades many short-lived proteins that are labeled with an ubiquitin chain. The identification of phosphorylation sites on the proteasome subunits suggests that degradation of these substrates can also be regulated at the proteasome. In yeast and humans, the unstructured C-terminal r...

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Detalles Bibliográficos
Autores principales: Wani, Prashant S., Suppahia, Anjana, Capalla, Xavier, Ondracek, Alex, Roelofs, Jeroen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908598/
https://www.ncbi.nlm.nih.gov/pubmed/27302526
http://dx.doi.org/10.1038/srep27873

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