Nuclear factor erythroid 2-related factor 2 is a critical target for the treatment of glucocorticoid-resistant lupus nephritis

BACKGROUND: Dimethyl fumarate (DMF), a nuclear factor erythroid 2-related factor 2 (Nrf2) activator, has been proven effective for the systemic treatment of multiple sclerosis. The aim of this study is to evaluate the anti-inflammatory effects of Nrf2 activators on human renal mesangial cells (HRMCs...

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Detalles Bibliográficos
Autores principales: Ebihara, Shin, Tajima, Hideaki, Ono, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908698/
https://www.ncbi.nlm.nih.gov/pubmed/27301376
http://dx.doi.org/10.1186/s13075-016-1039-5

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