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Virus-like particles derived from Pichia pastoris-expressed dengue virus type 1 glycoprotein elicit homotypic virus-neutralizing envelope domain III-directed antibodies

BACKGROUND: Four antigenically distinct serotypes (1–4) of dengue viruses (DENVs) cause dengue disease. Antibodies to any one DENV serotype have the potential to predispose an individual to more severe disease upon infection with a different DENV serotype. A dengue vaccine must elicit homotypic neut...

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Detalles Bibliográficos
Autores principales:	Poddar, Ankur, Ramasamy, Viswanathan, Shukla, Rahul, Rajpoot, Ravi Kant, Arora, Upasana, Jain, Swatantra K., Swaminathan, Sathyamangalam, Khanna, Navin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908714/ https://www.ncbi.nlm.nih.gov/pubmed/27301568 http://dx.doi.org/10.1186/s12896-016-0280-y

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