Directions for new developments on statistical design and analysis of small population group trials

BACKGROUND: Most statistical design and analysis methods for clinical trials have been developed and evaluated where at least several hundreds of patients could be recruited. These methods may not be suitable to evaluate therapies if the sample size is unavoidably small, which is usually termed by s...

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Detalles Bibliográficos
Autores principales: Hilgers, Ralf-Dieter, Roes, Kit, Stallard, Nigel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Position Statement
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908723/
https://www.ncbi.nlm.nih.gov/pubmed/27301273
http://dx.doi.org/10.1186/s13023-016-0464-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908723/
https://www.ncbi.nlm.nih.gov/pubmed/27301273
http://dx.doi.org/10.1186/s13023-016-0464-5

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