Cargando…
Anticoagulation Management in Patients with Pacemaker-Detected Atrial Fibrillation
INTRODUCTION: In patients with an implanted pacemaker, asymptomatic atrial fibrillation (AF) is associated with an increased risk of thrombo-embolic complications. There is still no consensus which duration of episodes of atrial fibrillation should be taken as an indicator for inclusion of oral anti...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Institute of Immunobiology and Human Genetics
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908739/ https://www.ncbi.nlm.nih.gov/pubmed/27335594 http://dx.doi.org/10.3889/oamjms.2016.053 |
_version_ | 1782437735721598976 |
---|---|
author | Poposka, Lidija Boskov, Vladimir Risteski, Dejan Taleski, Jane Georgievska-Ismail, Ljubica |
author_facet | Poposka, Lidija Boskov, Vladimir Risteski, Dejan Taleski, Jane Georgievska-Ismail, Ljubica |
author_sort | Poposka, Lidija |
collection | PubMed |
description | INTRODUCTION: In patients with an implanted pacemaker, asymptomatic atrial fibrillation (AF) is associated with an increased risk of thrombo-embolic complications. There is still no consensus which duration of episodes of atrial fibrillation should be taken as an indicator for inclusion of oral anticoagulation therapy (OAC). MATERIAL AND METHODS: A total of 104 patients who had no AF episodes in the past and have an indication for permanent pacing were included in the study. RESULTS: During an average follow-up of 18 months, 33 of the patients developed episodes of AF. Inclusion of OAC was performed in 17 patients, in whom AF was recorded, although in all patients CHA2DS2-VASc score was ≥ 1. The inclusion of OAC showed a statistically significant correlation with increasing duration of episodes of AF (r = 0.502, p = 0.003). During the follow-up period none of the patients developed thrombo-embolic complication. CONCLUSION: Considering that our group of patients had no thrombo-embolic events, we could conclude that dividing the AF episodes in less than 1% in 24 hours and longer than 1% within 24 hours could be an indicator for decision-making to include OAK if the CHA2DS2-VASc score is ≥ 1. |
format | Online Article Text |
id | pubmed-4908739 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Institute of Immunobiology and Human Genetics |
record_format | MEDLINE/PubMed |
spelling | pubmed-49087392016-06-22 Anticoagulation Management in Patients with Pacemaker-Detected Atrial Fibrillation Poposka, Lidija Boskov, Vladimir Risteski, Dejan Taleski, Jane Georgievska-Ismail, Ljubica Open Access Maced J Med Sci Clinical Science INTRODUCTION: In patients with an implanted pacemaker, asymptomatic atrial fibrillation (AF) is associated with an increased risk of thrombo-embolic complications. There is still no consensus which duration of episodes of atrial fibrillation should be taken as an indicator for inclusion of oral anticoagulation therapy (OAC). MATERIAL AND METHODS: A total of 104 patients who had no AF episodes in the past and have an indication for permanent pacing were included in the study. RESULTS: During an average follow-up of 18 months, 33 of the patients developed episodes of AF. Inclusion of OAC was performed in 17 patients, in whom AF was recorded, although in all patients CHA2DS2-VASc score was ≥ 1. The inclusion of OAC showed a statistically significant correlation with increasing duration of episodes of AF (r = 0.502, p = 0.003). During the follow-up period none of the patients developed thrombo-embolic complication. CONCLUSION: Considering that our group of patients had no thrombo-embolic events, we could conclude that dividing the AF episodes in less than 1% in 24 hours and longer than 1% within 24 hours could be an indicator for decision-making to include OAK if the CHA2DS2-VASc score is ≥ 1. Institute of Immunobiology and Human Genetics 2016-06-15 2016-04-20 /pmc/articles/PMC4908739/ /pubmed/27335594 http://dx.doi.org/10.3889/oamjms.2016.053 Text en Copyright: © 2016 Lidija Poposka, Vladimir Boskov, Dejan Risteski, Jane Taleski, Ljubica Georgievska-Ismail. http://creativecommons.org/licenses/by/2.5/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Clinical Science Poposka, Lidija Boskov, Vladimir Risteski, Dejan Taleski, Jane Georgievska-Ismail, Ljubica Anticoagulation Management in Patients with Pacemaker-Detected Atrial Fibrillation |
title | Anticoagulation Management in Patients with Pacemaker-Detected Atrial Fibrillation |
title_full | Anticoagulation Management in Patients with Pacemaker-Detected Atrial Fibrillation |
title_fullStr | Anticoagulation Management in Patients with Pacemaker-Detected Atrial Fibrillation |
title_full_unstemmed | Anticoagulation Management in Patients with Pacemaker-Detected Atrial Fibrillation |
title_short | Anticoagulation Management in Patients with Pacemaker-Detected Atrial Fibrillation |
title_sort | anticoagulation management in patients with pacemaker-detected atrial fibrillation |
topic | Clinical Science |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908739/ https://www.ncbi.nlm.nih.gov/pubmed/27335594 http://dx.doi.org/10.3889/oamjms.2016.053 |
work_keys_str_mv | AT poposkalidija anticoagulationmanagementinpatientswithpacemakerdetectedatrialfibrillation AT boskovvladimir anticoagulationmanagementinpatientswithpacemakerdetectedatrialfibrillation AT risteskidejan anticoagulationmanagementinpatientswithpacemakerdetectedatrialfibrillation AT taleskijane anticoagulationmanagementinpatientswithpacemakerdetectedatrialfibrillation AT georgievskaismailljubica anticoagulationmanagementinpatientswithpacemakerdetectedatrialfibrillation |