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Anticoagulation Management in Patients with Pacemaker-Detected Atrial Fibrillation

INTRODUCTION: In patients with an implanted pacemaker, asymptomatic atrial fibrillation (AF) is associated with an increased risk of thrombo-embolic complications. There is still no consensus which duration of episodes of atrial fibrillation should be taken as an indicator for inclusion of oral anti...

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Autores principales: Poposka, Lidija, Boskov, Vladimir, Risteski, Dejan, Taleski, Jane, Georgievska-Ismail, Ljubica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Institute of Immunobiology and Human Genetics 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908739/
https://www.ncbi.nlm.nih.gov/pubmed/27335594
http://dx.doi.org/10.3889/oamjms.2016.053
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author Poposka, Lidija
Boskov, Vladimir
Risteski, Dejan
Taleski, Jane
Georgievska-Ismail, Ljubica
author_facet Poposka, Lidija
Boskov, Vladimir
Risteski, Dejan
Taleski, Jane
Georgievska-Ismail, Ljubica
author_sort Poposka, Lidija
collection PubMed
description INTRODUCTION: In patients with an implanted pacemaker, asymptomatic atrial fibrillation (AF) is associated with an increased risk of thrombo-embolic complications. There is still no consensus which duration of episodes of atrial fibrillation should be taken as an indicator for inclusion of oral anticoagulation therapy (OAC). MATERIAL AND METHODS: A total of 104 patients who had no AF episodes in the past and have an indication for permanent pacing were included in the study. RESULTS: During an average follow-up of 18 months, 33 of the patients developed episodes of AF. Inclusion of OAC was performed in 17 patients, in whom AF was recorded, although in all patients CHA2DS2-VASc score was ≥ 1. The inclusion of OAC showed a statistically significant correlation with increasing duration of episodes of AF (r = 0.502, p = 0.003). During the follow-up period none of the patients developed thrombo-embolic complication. CONCLUSION: Considering that our group of patients had no thrombo-embolic events, we could conclude that dividing the AF episodes in less than 1% in 24 hours and longer than 1% within 24 hours could be an indicator for decision-making to include OAK if the CHA2DS2-VASc score is ≥ 1.
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spelling pubmed-49087392016-06-22 Anticoagulation Management in Patients with Pacemaker-Detected Atrial Fibrillation Poposka, Lidija Boskov, Vladimir Risteski, Dejan Taleski, Jane Georgievska-Ismail, Ljubica Open Access Maced J Med Sci Clinical Science INTRODUCTION: In patients with an implanted pacemaker, asymptomatic atrial fibrillation (AF) is associated with an increased risk of thrombo-embolic complications. There is still no consensus which duration of episodes of atrial fibrillation should be taken as an indicator for inclusion of oral anticoagulation therapy (OAC). MATERIAL AND METHODS: A total of 104 patients who had no AF episodes in the past and have an indication for permanent pacing were included in the study. RESULTS: During an average follow-up of 18 months, 33 of the patients developed episodes of AF. Inclusion of OAC was performed in 17 patients, in whom AF was recorded, although in all patients CHA2DS2-VASc score was ≥ 1. The inclusion of OAC showed a statistically significant correlation with increasing duration of episodes of AF (r = 0.502, p = 0.003). During the follow-up period none of the patients developed thrombo-embolic complication. CONCLUSION: Considering that our group of patients had no thrombo-embolic events, we could conclude that dividing the AF episodes in less than 1% in 24 hours and longer than 1% within 24 hours could be an indicator for decision-making to include OAK if the CHA2DS2-VASc score is ≥ 1. Institute of Immunobiology and Human Genetics 2016-06-15 2016-04-20 /pmc/articles/PMC4908739/ /pubmed/27335594 http://dx.doi.org/10.3889/oamjms.2016.053 Text en Copyright: © 2016 Lidija Poposka, Vladimir Boskov, Dejan Risteski, Jane Taleski, Ljubica Georgievska-Ismail. http://creativecommons.org/licenses/by/2.5/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Clinical Science
Poposka, Lidija
Boskov, Vladimir
Risteski, Dejan
Taleski, Jane
Georgievska-Ismail, Ljubica
Anticoagulation Management in Patients with Pacemaker-Detected Atrial Fibrillation
title Anticoagulation Management in Patients with Pacemaker-Detected Atrial Fibrillation
title_full Anticoagulation Management in Patients with Pacemaker-Detected Atrial Fibrillation
title_fullStr Anticoagulation Management in Patients with Pacemaker-Detected Atrial Fibrillation
title_full_unstemmed Anticoagulation Management in Patients with Pacemaker-Detected Atrial Fibrillation
title_short Anticoagulation Management in Patients with Pacemaker-Detected Atrial Fibrillation
title_sort anticoagulation management in patients with pacemaker-detected atrial fibrillation
topic Clinical Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908739/
https://www.ncbi.nlm.nih.gov/pubmed/27335594
http://dx.doi.org/10.3889/oamjms.2016.053
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