Cargando…

The Level of Cholesterol in COPD Patients with Severe and Very Severe Stage of the Disease

BACKGROUND: High blood cholesterol is part of metabolic syndrome and can be caused by medical conditions or bad dietary habits. AIM: The aim of the study was to investigate the prevalence of hypercholesterolemia in privies diagnosed patients with the severe and very severe stage of COPD, which were...

Descripción completa

Detalles Bibliográficos
Autores principales: Zafirova-Ivanovska, Beti, Stojkovikj, Jagoda, Dokikj, Dejan, Anastasova, Sasha, Debresliovska, Angela, Zejnel, Sead, Stojkovikj, Dragana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Institute of Immunobiology and Human Genetics 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908745/
https://www.ncbi.nlm.nih.gov/pubmed/27335600
http://dx.doi.org/10.3889/oamjms.2016.063
_version_ 1782437737124593664
author Zafirova-Ivanovska, Beti
Stojkovikj, Jagoda
Dokikj, Dejan
Anastasova, Sasha
Debresliovska, Angela
Zejnel, Sead
Stojkovikj, Dragana
author_facet Zafirova-Ivanovska, Beti
Stojkovikj, Jagoda
Dokikj, Dejan
Anastasova, Sasha
Debresliovska, Angela
Zejnel, Sead
Stojkovikj, Dragana
author_sort Zafirova-Ivanovska, Beti
collection PubMed
description BACKGROUND: High blood cholesterol is part of metabolic syndrome and can be caused by medical conditions or bad dietary habits. AIM: The aim of the study was to investigate the prevalence of hypercholesterolemia in privies diagnosed patients with the severe and very severe stage of COPD, which were stable. MATERIAL AND METHODS: We investigated 100 subjects, all of them smokers, with smoking status >10 years, stratified into two groups: with severe and very severe stage of the disease. It was clinical, randomized, cross-sectional study. Besides demographic parameters and functional parameters, body mass index, cholesterol, LDL, and HDL were investigated. RESULTS: In the group of patients with very severe COPD were recorded significantly higher average values of cholesterol (6.16 ± 1.5 vs. 5.61 ± 1.1, p = 0.039). As independent significant factors influencing cholesterol in the group with a very severe COPD were confirmed the age of the patients (p = 0.005), LDL (p = 0.004) and HDL (p = 0.002). In the group with severe COPD, only LDL was confirmed as an independent significant factor that has an impact on cholesterol (p < 0.0001). CONCLUSION: The results of our survey demonstrated a high level of blood cholesterol and LDL, and low level of blood HDL in both investigated group’s patients with COPD.
format Online
Article
Text
id pubmed-4908745
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Institute of Immunobiology and Human Genetics
record_format MEDLINE/PubMed
spelling pubmed-49087452016-06-22 The Level of Cholesterol in COPD Patients with Severe and Very Severe Stage of the Disease Zafirova-Ivanovska, Beti Stojkovikj, Jagoda Dokikj, Dejan Anastasova, Sasha Debresliovska, Angela Zejnel, Sead Stojkovikj, Dragana Open Access Maced J Med Sci Clinical Science BACKGROUND: High blood cholesterol is part of metabolic syndrome and can be caused by medical conditions or bad dietary habits. AIM: The aim of the study was to investigate the prevalence of hypercholesterolemia in privies diagnosed patients with the severe and very severe stage of COPD, which were stable. MATERIAL AND METHODS: We investigated 100 subjects, all of them smokers, with smoking status >10 years, stratified into two groups: with severe and very severe stage of the disease. It was clinical, randomized, cross-sectional study. Besides demographic parameters and functional parameters, body mass index, cholesterol, LDL, and HDL were investigated. RESULTS: In the group of patients with very severe COPD were recorded significantly higher average values of cholesterol (6.16 ± 1.5 vs. 5.61 ± 1.1, p = 0.039). As independent significant factors influencing cholesterol in the group with a very severe COPD were confirmed the age of the patients (p = 0.005), LDL (p = 0.004) and HDL (p = 0.002). In the group with severe COPD, only LDL was confirmed as an independent significant factor that has an impact on cholesterol (p < 0.0001). CONCLUSION: The results of our survey demonstrated a high level of blood cholesterol and LDL, and low level of blood HDL in both investigated group’s patients with COPD. Institute of Immunobiology and Human Genetics 2016-06-15 2016-05-24 /pmc/articles/PMC4908745/ /pubmed/27335600 http://dx.doi.org/10.3889/oamjms.2016.063 Text en Copyright: © 2016 Beti Zafirova-Ivanovska, Jagoda Stojkovikj, Dejan Dokikj, Sasha Anastasova, Angela Debresliovska, Sead Zejnel, Dragana Stojkovikj. http://creativecommons.org/licenses/by/2.5/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Clinical Science
Zafirova-Ivanovska, Beti
Stojkovikj, Jagoda
Dokikj, Dejan
Anastasova, Sasha
Debresliovska, Angela
Zejnel, Sead
Stojkovikj, Dragana
The Level of Cholesterol in COPD Patients with Severe and Very Severe Stage of the Disease
title The Level of Cholesterol in COPD Patients with Severe and Very Severe Stage of the Disease
title_full The Level of Cholesterol in COPD Patients with Severe and Very Severe Stage of the Disease
title_fullStr The Level of Cholesterol in COPD Patients with Severe and Very Severe Stage of the Disease
title_full_unstemmed The Level of Cholesterol in COPD Patients with Severe and Very Severe Stage of the Disease
title_short The Level of Cholesterol in COPD Patients with Severe and Very Severe Stage of the Disease
title_sort level of cholesterol in copd patients with severe and very severe stage of the disease
topic Clinical Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908745/
https://www.ncbi.nlm.nih.gov/pubmed/27335600
http://dx.doi.org/10.3889/oamjms.2016.063
work_keys_str_mv AT zafirovaivanovskabeti thelevelofcholesterolincopdpatientswithsevereandveryseverestageofthedisease
AT stojkovikjjagoda thelevelofcholesterolincopdpatientswithsevereandveryseverestageofthedisease
AT dokikjdejan thelevelofcholesterolincopdpatientswithsevereandveryseverestageofthedisease
AT anastasovasasha thelevelofcholesterolincopdpatientswithsevereandveryseverestageofthedisease
AT debresliovskaangela thelevelofcholesterolincopdpatientswithsevereandveryseverestageofthedisease
AT zejnelsead thelevelofcholesterolincopdpatientswithsevereandveryseverestageofthedisease
AT stojkovikjdragana thelevelofcholesterolincopdpatientswithsevereandveryseverestageofthedisease
AT zafirovaivanovskabeti levelofcholesterolincopdpatientswithsevereandveryseverestageofthedisease
AT stojkovikjjagoda levelofcholesterolincopdpatientswithsevereandveryseverestageofthedisease
AT dokikjdejan levelofcholesterolincopdpatientswithsevereandveryseverestageofthedisease
AT anastasovasasha levelofcholesterolincopdpatientswithsevereandveryseverestageofthedisease
AT debresliovskaangela levelofcholesterolincopdpatientswithsevereandveryseverestageofthedisease
AT zejnelsead levelofcholesterolincopdpatientswithsevereandveryseverestageofthedisease
AT stojkovikjdragana levelofcholesterolincopdpatientswithsevereandveryseverestageofthedisease