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The Level of Cholesterol in COPD Patients with Severe and Very Severe Stage of the Disease
BACKGROUND: High blood cholesterol is part of metabolic syndrome and can be caused by medical conditions or bad dietary habits. AIM: The aim of the study was to investigate the prevalence of hypercholesterolemia in privies diagnosed patients with the severe and very severe stage of COPD, which were...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Institute of Immunobiology and Human Genetics
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908745/ https://www.ncbi.nlm.nih.gov/pubmed/27335600 http://dx.doi.org/10.3889/oamjms.2016.063 |
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author | Zafirova-Ivanovska, Beti Stojkovikj, Jagoda Dokikj, Dejan Anastasova, Sasha Debresliovska, Angela Zejnel, Sead Stojkovikj, Dragana |
author_facet | Zafirova-Ivanovska, Beti Stojkovikj, Jagoda Dokikj, Dejan Anastasova, Sasha Debresliovska, Angela Zejnel, Sead Stojkovikj, Dragana |
author_sort | Zafirova-Ivanovska, Beti |
collection | PubMed |
description | BACKGROUND: High blood cholesterol is part of metabolic syndrome and can be caused by medical conditions or bad dietary habits. AIM: The aim of the study was to investigate the prevalence of hypercholesterolemia in privies diagnosed patients with the severe and very severe stage of COPD, which were stable. MATERIAL AND METHODS: We investigated 100 subjects, all of them smokers, with smoking status >10 years, stratified into two groups: with severe and very severe stage of the disease. It was clinical, randomized, cross-sectional study. Besides demographic parameters and functional parameters, body mass index, cholesterol, LDL, and HDL were investigated. RESULTS: In the group of patients with very severe COPD were recorded significantly higher average values of cholesterol (6.16 ± 1.5 vs. 5.61 ± 1.1, p = 0.039). As independent significant factors influencing cholesterol in the group with a very severe COPD were confirmed the age of the patients (p = 0.005), LDL (p = 0.004) and HDL (p = 0.002). In the group with severe COPD, only LDL was confirmed as an independent significant factor that has an impact on cholesterol (p < 0.0001). CONCLUSION: The results of our survey demonstrated a high level of blood cholesterol and LDL, and low level of blood HDL in both investigated group’s patients with COPD. |
format | Online Article Text |
id | pubmed-4908745 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Institute of Immunobiology and Human Genetics |
record_format | MEDLINE/PubMed |
spelling | pubmed-49087452016-06-22 The Level of Cholesterol in COPD Patients with Severe and Very Severe Stage of the Disease Zafirova-Ivanovska, Beti Stojkovikj, Jagoda Dokikj, Dejan Anastasova, Sasha Debresliovska, Angela Zejnel, Sead Stojkovikj, Dragana Open Access Maced J Med Sci Clinical Science BACKGROUND: High blood cholesterol is part of metabolic syndrome and can be caused by medical conditions or bad dietary habits. AIM: The aim of the study was to investigate the prevalence of hypercholesterolemia in privies diagnosed patients with the severe and very severe stage of COPD, which were stable. MATERIAL AND METHODS: We investigated 100 subjects, all of them smokers, with smoking status >10 years, stratified into two groups: with severe and very severe stage of the disease. It was clinical, randomized, cross-sectional study. Besides demographic parameters and functional parameters, body mass index, cholesterol, LDL, and HDL were investigated. RESULTS: In the group of patients with very severe COPD were recorded significantly higher average values of cholesterol (6.16 ± 1.5 vs. 5.61 ± 1.1, p = 0.039). As independent significant factors influencing cholesterol in the group with a very severe COPD were confirmed the age of the patients (p = 0.005), LDL (p = 0.004) and HDL (p = 0.002). In the group with severe COPD, only LDL was confirmed as an independent significant factor that has an impact on cholesterol (p < 0.0001). CONCLUSION: The results of our survey demonstrated a high level of blood cholesterol and LDL, and low level of blood HDL in both investigated group’s patients with COPD. Institute of Immunobiology and Human Genetics 2016-06-15 2016-05-24 /pmc/articles/PMC4908745/ /pubmed/27335600 http://dx.doi.org/10.3889/oamjms.2016.063 Text en Copyright: © 2016 Beti Zafirova-Ivanovska, Jagoda Stojkovikj, Dejan Dokikj, Sasha Anastasova, Angela Debresliovska, Sead Zejnel, Dragana Stojkovikj. http://creativecommons.org/licenses/by/2.5/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Clinical Science Zafirova-Ivanovska, Beti Stojkovikj, Jagoda Dokikj, Dejan Anastasova, Sasha Debresliovska, Angela Zejnel, Sead Stojkovikj, Dragana The Level of Cholesterol in COPD Patients with Severe and Very Severe Stage of the Disease |
title | The Level of Cholesterol in COPD Patients with Severe and Very Severe Stage of the Disease |
title_full | The Level of Cholesterol in COPD Patients with Severe and Very Severe Stage of the Disease |
title_fullStr | The Level of Cholesterol in COPD Patients with Severe and Very Severe Stage of the Disease |
title_full_unstemmed | The Level of Cholesterol in COPD Patients with Severe and Very Severe Stage of the Disease |
title_short | The Level of Cholesterol in COPD Patients with Severe and Very Severe Stage of the Disease |
title_sort | level of cholesterol in copd patients with severe and very severe stage of the disease |
topic | Clinical Science |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908745/ https://www.ncbi.nlm.nih.gov/pubmed/27335600 http://dx.doi.org/10.3889/oamjms.2016.063 |
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