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CHiCAGO: robust detection of DNA looping interactions in Capture Hi-C data

Capture Hi-C (CHi-C) is a method for profiling chromosomal interactions involving targeted regions of interest, such as gene promoters, globally and at high resolution. Signal detection in CHi-C data involves a number of statistical challenges that are not observed when using other Hi-C-like techniq...

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Detalles Bibliográficos
Autores principales: Cairns, Jonathan, Freire-Pritchett, Paula, Wingett, Steven W., Várnai, Csilla, Dimond, Andrew, Plagnol, Vincent, Zerbino, Daniel, Schoenfelder, Stefan, Javierre, Biola-Maria, Osborne, Cameron, Fraser, Peter, Spivakov, Mikhail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908757/
https://www.ncbi.nlm.nih.gov/pubmed/27306882
http://dx.doi.org/10.1186/s13059-016-0992-2