Quantitation of CDH1 promoter methylation in formalin-fixed paraffin-embedded tissues of breast cancer patients using differential high resolution melting analysis

BACKGROUND: E-cadherin (CDH1) plays an important role in cell–cell adhesion of epithelial tissues. Loss of E-cadherin expression can lead to loss of tissue integrity, metastasis, and cancer progression. Also loss of E-cadherin expression might be related to aberrant promoter methylation of the CDH1...

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Detalles Bibliográficos
Autores principales: Naghitorabi, Mojgan, Mohammadi-Asl, Javad, Sadeghi, Hamid Mir Mohammad, Rabbani, Mohammad, Jafarian-Dehkordi, Abbas, Javanmard, Shaghayegh Haghjooy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908786/
https://www.ncbi.nlm.nih.gov/pubmed/27308263
http://dx.doi.org/10.4103/2277-9175.183139

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