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Leprosy in children and adolescents under 15 years old in an urban centre in Brazil

This original study describes the intra-urban distribution of cases of leprosy in residents under 15 years old in Salvador, Bahia, Brazil; the study also identifies the environment in which Mycobacterium leprae is being transmitted. The cases were distributed by operational classification, clinical...

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Autores principales: Santos, Selton Diniz, Penna, Gerson Oliveira, Costa, Maria da Conceição Nascimento, Natividade, Marcio Santos, Teixeira, Maria Glória
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909033/
https://www.ncbi.nlm.nih.gov/pubmed/27223655
http://dx.doi.org/10.1590/0074-02760160002
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author Santos, Selton Diniz
Penna, Gerson Oliveira
Costa, Maria da Conceição Nascimento
Natividade, Marcio Santos
Teixeira, Maria Glória
author_facet Santos, Selton Diniz
Penna, Gerson Oliveira
Costa, Maria da Conceição Nascimento
Natividade, Marcio Santos
Teixeira, Maria Glória
author_sort Santos, Selton Diniz
collection PubMed
description This original study describes the intra-urban distribution of cases of leprosy in residents under 15 years old in Salvador, Bahia, Brazil; the study also identifies the environment in which Mycobacterium leprae is being transmitted. The cases were distributed by operational classification, clinical forms, type of contact and the addresses were geo-referenced by neighborhood. Between 2007 and 2011, were reported 145 cases of leprosy in target population living in Salvador, corresponding to detection rates of 6.21, 6.14, 5.58, 5.41 and 6.88/100,000 inhabitants, respectively. The spatial distribution of the disease was focal. Of the 157 neighborhoods of Salvador, 44 (28.6%) notified cases of leprosy and in 22 (50%) of these were detected more than 10 cases per 100,000 inhabitants. The infectious forms were found in 40% of cases. Over 90% of cases had been living in Salvador for more than five years. Overall, 52.6% reported having had contact with another infected individual inside the household and 25% in their social circle. In Salvador, M. leprae transmission is established. The situation is a major concern, since transmission is intense at an early age, indicating that this endemic disease is expanding and contacts extend beyond individual households.
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spelling pubmed-49090332016-06-16 Leprosy in children and adolescents under 15 years old in an urban centre in Brazil Santos, Selton Diniz Penna, Gerson Oliveira Costa, Maria da Conceição Nascimento Natividade, Marcio Santos Teixeira, Maria Glória Mem Inst Oswaldo Cruz Articles This original study describes the intra-urban distribution of cases of leprosy in residents under 15 years old in Salvador, Bahia, Brazil; the study also identifies the environment in which Mycobacterium leprae is being transmitted. The cases were distributed by operational classification, clinical forms, type of contact and the addresses were geo-referenced by neighborhood. Between 2007 and 2011, were reported 145 cases of leprosy in target population living in Salvador, corresponding to detection rates of 6.21, 6.14, 5.58, 5.41 and 6.88/100,000 inhabitants, respectively. The spatial distribution of the disease was focal. Of the 157 neighborhoods of Salvador, 44 (28.6%) notified cases of leprosy and in 22 (50%) of these were detected more than 10 cases per 100,000 inhabitants. The infectious forms were found in 40% of cases. Over 90% of cases had been living in Salvador for more than five years. Overall, 52.6% reported having had contact with another infected individual inside the household and 25% in their social circle. In Salvador, M. leprae transmission is established. The situation is a major concern, since transmission is intense at an early age, indicating that this endemic disease is expanding and contacts extend beyond individual households. Instituto Oswaldo Cruz, Ministério da Saúde 2016-06 /pmc/articles/PMC4909033/ /pubmed/27223655 http://dx.doi.org/10.1590/0074-02760160002 Text en http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Articles
Santos, Selton Diniz
Penna, Gerson Oliveira
Costa, Maria da Conceição Nascimento
Natividade, Marcio Santos
Teixeira, Maria Glória
Leprosy in children and adolescents under 15 years old in an urban centre in Brazil
title Leprosy in children and adolescents under 15 years old in an urban centre in Brazil
title_full Leprosy in children and adolescents under 15 years old in an urban centre in Brazil
title_fullStr Leprosy in children and adolescents under 15 years old in an urban centre in Brazil
title_full_unstemmed Leprosy in children and adolescents under 15 years old in an urban centre in Brazil
title_short Leprosy in children and adolescents under 15 years old in an urban centre in Brazil
title_sort leprosy in children and adolescents under 15 years old in an urban centre in brazil
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909033/
https://www.ncbi.nlm.nih.gov/pubmed/27223655
http://dx.doi.org/10.1590/0074-02760160002
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