Cargando…

Does Glaucoma Share Common Pathogenesis with Branch Retinal Vein Occlusion?

BACKGROUND: To evaluate the observed prevalence and the optic nerve head (ONH) characteristics of normal tension glaucoma (NTG)-suspect eyes in branch retinal vein occulusion (BRVO) eyes in Korean population. METHODS: This was a retrospective observational study. We investigated 445 BRVO eyes that w...

Descripción completa

Detalles Bibliográficos
Autores principales: Han, Jong Chul, Eo, Doo Ri, Lee, Taek Kwan, Shin, Jong Hoon, Kee, Changwon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909192/
https://www.ncbi.nlm.nih.gov/pubmed/27304065
http://dx.doi.org/10.1371/journal.pone.0156966
_version_ 1782437795292250112
author Han, Jong Chul
Eo, Doo Ri
Lee, Taek Kwan
Shin, Jong Hoon
Kee, Changwon
author_facet Han, Jong Chul
Eo, Doo Ri
Lee, Taek Kwan
Shin, Jong Hoon
Kee, Changwon
author_sort Han, Jong Chul
collection PubMed
description BACKGROUND: To evaluate the observed prevalence and the optic nerve head (ONH) characteristics of normal tension glaucoma (NTG)-suspect eyes in branch retinal vein occulusion (BRVO) eyes in Korean population. METHODS: This was a retrospective observational study. We investigated 445 BRVO eyes that were diagnosed in the retina clinic of Samsung Medical Center between March 2005 and December 2011. The observed prevalence of NTG-suspect in BRVO eyes was evaluated compared to the previous population based study. In addition, NTG-suspect cases in BRVO were divided into three groups based on the characteristics of optic disc morphology. RESULTS: In 445 BRVO eyes, 30 eyes were excluded from the present study. In 415 BRVO eyes, 4.3% (18 eyes) (95% confident interval [CI], 2.4–6.3%) were diagnosed with suspect glaucoma and this is not significantly different from the result in the general Korean population (P = 0.09). We classified the NTG-suspect eyes into three groups such as disc rim notching and thinning type (Group 1; 55.6%), optic cup-sited hemorrhage type (Group 2; 16.7%) and disc rim thinning and pallor type (Group 3; 27.8%). NTG-suspect in the fellow eye were only found in group 1 (80%) and group 2 (67%), but not in group 3 (P = 0.01). CONCLUSIONS: BRVO and glaucoma seem to have no common vascular pathogenesis in consideration of the prevalence of NTG-suspect in BRVO eyes compared to general Korean population.
format Online
Article
Text
id pubmed-4909192
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-49091922016-07-06 Does Glaucoma Share Common Pathogenesis with Branch Retinal Vein Occlusion? Han, Jong Chul Eo, Doo Ri Lee, Taek Kwan Shin, Jong Hoon Kee, Changwon PLoS One Research Article BACKGROUND: To evaluate the observed prevalence and the optic nerve head (ONH) characteristics of normal tension glaucoma (NTG)-suspect eyes in branch retinal vein occulusion (BRVO) eyes in Korean population. METHODS: This was a retrospective observational study. We investigated 445 BRVO eyes that were diagnosed in the retina clinic of Samsung Medical Center between March 2005 and December 2011. The observed prevalence of NTG-suspect in BRVO eyes was evaluated compared to the previous population based study. In addition, NTG-suspect cases in BRVO were divided into three groups based on the characteristics of optic disc morphology. RESULTS: In 445 BRVO eyes, 30 eyes were excluded from the present study. In 415 BRVO eyes, 4.3% (18 eyes) (95% confident interval [CI], 2.4–6.3%) were diagnosed with suspect glaucoma and this is not significantly different from the result in the general Korean population (P = 0.09). We classified the NTG-suspect eyes into three groups such as disc rim notching and thinning type (Group 1; 55.6%), optic cup-sited hemorrhage type (Group 2; 16.7%) and disc rim thinning and pallor type (Group 3; 27.8%). NTG-suspect in the fellow eye were only found in group 1 (80%) and group 2 (67%), but not in group 3 (P = 0.01). CONCLUSIONS: BRVO and glaucoma seem to have no common vascular pathogenesis in consideration of the prevalence of NTG-suspect in BRVO eyes compared to general Korean population. Public Library of Science 2016-06-15 /pmc/articles/PMC4909192/ /pubmed/27304065 http://dx.doi.org/10.1371/journal.pone.0156966 Text en © 2016 Han et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Han, Jong Chul
Eo, Doo Ri
Lee, Taek Kwan
Shin, Jong Hoon
Kee, Changwon
Does Glaucoma Share Common Pathogenesis with Branch Retinal Vein Occlusion?
title Does Glaucoma Share Common Pathogenesis with Branch Retinal Vein Occlusion?
title_full Does Glaucoma Share Common Pathogenesis with Branch Retinal Vein Occlusion?
title_fullStr Does Glaucoma Share Common Pathogenesis with Branch Retinal Vein Occlusion?
title_full_unstemmed Does Glaucoma Share Common Pathogenesis with Branch Retinal Vein Occlusion?
title_short Does Glaucoma Share Common Pathogenesis with Branch Retinal Vein Occlusion?
title_sort does glaucoma share common pathogenesis with branch retinal vein occlusion?
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909192/
https://www.ncbi.nlm.nih.gov/pubmed/27304065
http://dx.doi.org/10.1371/journal.pone.0156966
work_keys_str_mv AT hanjongchul doesglaucomasharecommonpathogenesiswithbranchretinalveinocclusion
AT eodoori doesglaucomasharecommonpathogenesiswithbranchretinalveinocclusion
AT leetaekkwan doesglaucomasharecommonpathogenesiswithbranchretinalveinocclusion
AT shinjonghoon doesglaucomasharecommonpathogenesiswithbranchretinalveinocclusion
AT keechangwon doesglaucomasharecommonpathogenesiswithbranchretinalveinocclusion