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Inherited Disease Genetics Improves the Identification of Cancer-Associated Genes
The identification of biologically significant variants in cancer genomes is critical to therapeutic discovery, but it is limited by the statistical power needed to discern driver from passenger. Independent biological data can be used to filter cancer exomes and increase statistical power. Large ge...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909226/ https://www.ncbi.nlm.nih.gov/pubmed/27304678 http://dx.doi.org/10.1371/journal.pgen.1006081 |