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Inherited Disease Genetics Improves the Identification of Cancer-Associated Genes

The identification of biologically significant variants in cancer genomes is critical to therapeutic discovery, but it is limited by the statistical power needed to discern driver from passenger. Independent biological data can be used to filter cancer exomes and increase statistical power. Large ge...

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Detalles Bibliográficos
Autores principales: Zhao, Boyang, Pritchard, Justin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909226/
https://www.ncbi.nlm.nih.gov/pubmed/27304678
http://dx.doi.org/10.1371/journal.pgen.1006081