Exogenous Alpha-Synuclein Alters Pre- and Post-Synaptic Activity by Fragmenting Lipid Rafts

Alpha-synuclein (αSyn) interferes with multiple steps of synaptic activity at pre-and post-synaptic terminals, however the mechanism/s by which αSyn alters neurotransmitter release and synaptic potentiation is unclear. By atomic force microscopy we show that human αSyn, when incubated with reconstit...

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Detalles Bibliográficos
Autores principales: Emanuele, Marco, Esposito, Alessandro, Camerini, Serena, Antonucci, Flavia, Ferrara, Silvia, Seghezza, Silvia, Catelani, Tiziano, Crescenzi, Marco, Marotta, Roberto, Canale, Claudio, Matteoli, Michela, Menna, Elisabetta, Chieregatti, Evelina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909369/
https://www.ncbi.nlm.nih.gov/pubmed/27322472
http://dx.doi.org/10.1016/j.ebiom.2016.03.038

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