Spatiotemporal plasticity of miRNAs functions: The miR-17-92 case

The functional effect of a specific miRNA is tightly linked to the transcriptome, thus having the potential to elicit distinct outcomes in different cellular states. Our recent discovery of a dual role of the miR-17-92 cluster, which shifts from oncogene to tumor suppressor during lymphoma progressi...

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Detalles Bibliográficos
Autores principales: Bonaldi, Tiziana, Mihailovich, Marija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909434/
https://www.ncbi.nlm.nih.gov/pubmed/27314099
http://dx.doi.org/10.1080/23723556.2016.1156216
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author Bonaldi, Tiziana
Mihailovich, Marija
author_facet Bonaldi, Tiziana
Mihailovich, Marija
author_sort Bonaldi, Tiziana
collection PubMed
description The functional effect of a specific miRNA is tightly linked to the transcriptome, thus having the potential to elicit distinct outcomes in different cellular states. Our recent discovery of a dual role of the miR-17-92 cluster, which shifts from oncogene to tumor suppressor during lymphoma progression, exemplifies the spatiotemporal plasticity of miRNAs.
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spelling pubmed-49094342017-04-15 Spatiotemporal plasticity of miRNAs functions: The miR-17-92 case Bonaldi, Tiziana Mihailovich, Marija Mol Cell Oncol Author's View The functional effect of a specific miRNA is tightly linked to the transcriptome, thus having the potential to elicit distinct outcomes in different cellular states. Our recent discovery of a dual role of the miR-17-92 cluster, which shifts from oncogene to tumor suppressor during lymphoma progression, exemplifies the spatiotemporal plasticity of miRNAs. Taylor & Francis 2016-04-15 /pmc/articles/PMC4909434/ /pubmed/27314099 http://dx.doi.org/10.1080/23723556.2016.1156216 Text en © 2016 The Author(s). Published with license by Taylor & Francis Group, LLC http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.
spellingShingle Author's View
Bonaldi, Tiziana
Mihailovich, Marija
Spatiotemporal plasticity of miRNAs functions: The miR-17-92 case
title Spatiotemporal plasticity of miRNAs functions: The miR-17-92 case
title_full Spatiotemporal plasticity of miRNAs functions: The miR-17-92 case
title_fullStr Spatiotemporal plasticity of miRNAs functions: The miR-17-92 case
title_full_unstemmed Spatiotemporal plasticity of miRNAs functions: The miR-17-92 case
title_short Spatiotemporal plasticity of miRNAs functions: The miR-17-92 case
title_sort spatiotemporal plasticity of mirnas functions: the mir-17-92 case
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909434/
https://www.ncbi.nlm.nih.gov/pubmed/27314099
http://dx.doi.org/10.1080/23723556.2016.1156216
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