A TAD closer to ATM

Ataxia telangiectasia mutated (ATM) has been known for decades as the main kinase mediating the DNA double-strand break response. Our recent findings suggest that its major role at the sites of breaks likely resides in its ability to modify both the local chromatin landscape and the global chromosom...

Descripción completa

Detalles Bibliográficos
Autores principales: Aymard, Francois, Legube, Gaëlle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909466/
https://www.ncbi.nlm.nih.gov/pubmed/27314089
http://dx.doi.org/10.1080/23723556.2015.1134411
_version_ 1782437837340147712
author Aymard, Francois
Legube, Gaëlle
author_facet Aymard, Francois
Legube, Gaëlle
author_sort Aymard, Francois
collection PubMed
description Ataxia telangiectasia mutated (ATM) has been known for decades as the main kinase mediating the DNA double-strand break response. Our recent findings suggest that its major role at the sites of breaks likely resides in its ability to modify both the local chromatin landscape and the global chromosome organization in order to promote repair accuracy.
format Online
Article
Text
id pubmed-4909466
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Taylor & Francis
record_format MEDLINE/PubMed
spelling pubmed-49094662017-03-10 A TAD closer to ATM Aymard, Francois Legube, Gaëlle Mol Cell Oncol Author's View Ataxia telangiectasia mutated (ATM) has been known for decades as the main kinase mediating the DNA double-strand break response. Our recent findings suggest that its major role at the sites of breaks likely resides in its ability to modify both the local chromatin landscape and the global chromosome organization in order to promote repair accuracy. Taylor & Francis 2016-03-10 /pmc/articles/PMC4909466/ /pubmed/27314089 http://dx.doi.org/10.1080/23723556.2015.1134411 Text en © 2016 The Author(s). Published with license by Taylor & Francis Group, LLC http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.
spellingShingle Author's View
Aymard, Francois
Legube, Gaëlle
A TAD closer to ATM
title A TAD closer to ATM
title_full A TAD closer to ATM
title_fullStr A TAD closer to ATM
title_full_unstemmed A TAD closer to ATM
title_short A TAD closer to ATM
title_sort tad closer to atm
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909466/
https://www.ncbi.nlm.nih.gov/pubmed/27314089
http://dx.doi.org/10.1080/23723556.2015.1134411
work_keys_str_mv AT aymardfrancois atadclosertoatm
AT legubegaelle atadclosertoatm
AT aymardfrancois tadclosertoatm
AT legubegaelle tadclosertoatm

Ejemplares similares