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Evaluation of corneal higher order aberrations in normal topographic patterns
PURPOSE: This study reports the characteristics of corneal higher order aberrations (HOAs) in eyes with normal topographic pattern using the Pentacam scheimpflug system. METHODS: In this prospective, observational, comparative study, 165 eyes of 97 patients separated into five groups based on cornea...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909702/ https://www.ncbi.nlm.nih.gov/pubmed/27331151 http://dx.doi.org/10.1016/j.joco.2016.03.001 |
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author | Mirzajani, Ali Aghataheri, Sattar Ghoreishi, Mohammad Jafarzadepour, Ebrahim Mohammadinia, Mohadese |
author_facet | Mirzajani, Ali Aghataheri, Sattar Ghoreishi, Mohammad Jafarzadepour, Ebrahim Mohammadinia, Mohadese |
author_sort | Mirzajani, Ali |
collection | PubMed |
description | PURPOSE: This study reports the characteristics of corneal higher order aberrations (HOAs) in eyes with normal topographic pattern using the Pentacam scheimpflug system. METHODS: In this prospective, observational, comparative study, 165 eyes of 97 patients separated into five groups based on corneal topographic patterns were enrolled. All eyes received a comprehensive ophthalmologic examination including corneal tomographic analysis with the Pentacam system. Keratometry, corneal cylinder, and corneal aberrometric data were recorded and analyzed. Root mean square values (RMS) were calculated for corneal HOAs up to the 6th order, total coma, total trefoil, total spherical aberration, total tetrafoil, and higher order astigmatism. Evaluation of these data to discriminate between the five groups was assessed using the analysis of variance test by Generalized Estimation Equation Linear Model. RESULTS: Corneal HOAs were found to be significantly higher for Asymmetric Bow Tie and Irregular groups than other groups (p = <0.001). RMS of total coma aberration ([Formula: see text] , [Formula: see text] , [Formula: see text] , [Formula: see text]) were significantly greater in the Asymmetric Bow Tie pattern than others, and RMS of total Spherical aberration ([Formula: see text] , [Formula: see text]) was significantly higher in the Irregular pattern than other groups (p = <0.001). The results of our study demonstrate that a tendency toward significant higher values of trefoil, tetrafoil, and higher order astigmatism in Irregular pattern (all p < 0.05). Significantly higher amounts of 3rd order RMS in Asymmetric Bow Tie group and 4th to 6th order RMS in Irregular pattern group were other outcomes of our study (p = <0.001). CONCLUSIONS: Based on results in this study, there were a good correlation between corneal topographic pattern and corneal HOAs in normal eyes. These results indicate that the corneal HOAs values are largely determined by the topographic patterns. A larger sample size would perhaps have been beneficial to yield in more accurate outcomes. |
format | Online Article Text |
id | pubmed-4909702 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-49097022016-06-21 Evaluation of corneal higher order aberrations in normal topographic patterns Mirzajani, Ali Aghataheri, Sattar Ghoreishi, Mohammad Jafarzadepour, Ebrahim Mohammadinia, Mohadese J Curr Ophthalmol Original Research PURPOSE: This study reports the characteristics of corneal higher order aberrations (HOAs) in eyes with normal topographic pattern using the Pentacam scheimpflug system. METHODS: In this prospective, observational, comparative study, 165 eyes of 97 patients separated into five groups based on corneal topographic patterns were enrolled. All eyes received a comprehensive ophthalmologic examination including corneal tomographic analysis with the Pentacam system. Keratometry, corneal cylinder, and corneal aberrometric data were recorded and analyzed. Root mean square values (RMS) were calculated for corneal HOAs up to the 6th order, total coma, total trefoil, total spherical aberration, total tetrafoil, and higher order astigmatism. Evaluation of these data to discriminate between the five groups was assessed using the analysis of variance test by Generalized Estimation Equation Linear Model. RESULTS: Corneal HOAs were found to be significantly higher for Asymmetric Bow Tie and Irregular groups than other groups (p = <0.001). RMS of total coma aberration ([Formula: see text] , [Formula: see text] , [Formula: see text] , [Formula: see text]) were significantly greater in the Asymmetric Bow Tie pattern than others, and RMS of total Spherical aberration ([Formula: see text] , [Formula: see text]) was significantly higher in the Irregular pattern than other groups (p = <0.001). The results of our study demonstrate that a tendency toward significant higher values of trefoil, tetrafoil, and higher order astigmatism in Irregular pattern (all p < 0.05). Significantly higher amounts of 3rd order RMS in Asymmetric Bow Tie group and 4th to 6th order RMS in Irregular pattern group were other outcomes of our study (p = <0.001). CONCLUSIONS: Based on results in this study, there were a good correlation between corneal topographic pattern and corneal HOAs in normal eyes. These results indicate that the corneal HOAs values are largely determined by the topographic patterns. A larger sample size would perhaps have been beneficial to yield in more accurate outcomes. Elsevier 2016-04-04 /pmc/articles/PMC4909702/ /pubmed/27331151 http://dx.doi.org/10.1016/j.joco.2016.03.001 Text en Copyright © 2016, Iranian Society of Ophthalmology. Production and hosting by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Original Research Mirzajani, Ali Aghataheri, Sattar Ghoreishi, Mohammad Jafarzadepour, Ebrahim Mohammadinia, Mohadese Evaluation of corneal higher order aberrations in normal topographic patterns |
title | Evaluation of corneal higher order aberrations in normal topographic patterns |
title_full | Evaluation of corneal higher order aberrations in normal topographic patterns |
title_fullStr | Evaluation of corneal higher order aberrations in normal topographic patterns |
title_full_unstemmed | Evaluation of corneal higher order aberrations in normal topographic patterns |
title_short | Evaluation of corneal higher order aberrations in normal topographic patterns |
title_sort | evaluation of corneal higher order aberrations in normal topographic patterns |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909702/ https://www.ncbi.nlm.nih.gov/pubmed/27331151 http://dx.doi.org/10.1016/j.joco.2016.03.001 |
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