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A Positive TGF-β/c-KIT Feedback Loop Drives Tumor Progression in Advanced Primary Liver Cancer()()

Hepatocellular carcinoma (HCC) is globally the second most common cause of cancer mortality. The majority of HCC patients are diagnosed at advanced stage disease for which no curative treatments exist. TGF-β has been identified as a potential therapeutic target. However, the molecular mechanisms med...

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Detalles Bibliográficos
Autores principales: Rojas, Andres, Zhang, Pingyu, Wang, Ying, Foo, Wai Chin, Muñoz, Nina M., Xiao, Lianchun, Wang, Jing, Gores, Gregory J., Hung, Mien-Chie, Blechacz, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909706/
https://www.ncbi.nlm.nih.gov/pubmed/27292026
http://dx.doi.org/10.1016/j.neo.2016.04.002

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