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A Positive TGF-β/c-KIT Feedback Loop Drives Tumor Progression in Advanced Primary Liver Cancer()()
Hepatocellular carcinoma (HCC) is globally the second most common cause of cancer mortality. The majority of HCC patients are diagnosed at advanced stage disease for which no curative treatments exist. TGF-β has been identified as a potential therapeutic target. However, the molecular mechanisms med...
Autores principales: | Rojas, Andres, Zhang, Pingyu, Wang, Ying, Foo, Wai Chin, Muñoz, Nina M., Xiao, Lianchun, Wang, Jing, Gores, Gregory J., Hung, Mien-Chie, Blechacz, Boris |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909706/ https://www.ncbi.nlm.nih.gov/pubmed/27292026 http://dx.doi.org/10.1016/j.neo.2016.04.002 |
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