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Efficient generation of monoclonal antibodies against peptide in the context of MHCII using magnetic enrichment

Monoclonal antibodies specific for foreign antigens, auto-antigens, allogeneic antigens and tumour neo-antigens in the context of major histocompatibility complex II (MHCII) are highly desirable as novel immunotherapeutics. However, there is no standard protocol for the efficient generation of monoc...

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Detalles Bibliográficos
Autores principales:	Spanier, Justin A., Frederick, Daniel R., Taylor, Justin J., Heffernan, James R., Kotov, Dmitri I., Martinov, Tijana, Osum, Kevin C., Ruggiero, Jenna L., Rust, Blake J., Landry, Samuel J., Jenkins, Marc K., McLachlan, James B., Fife, Brian T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909947/ https://www.ncbi.nlm.nih.gov/pubmed/27292946 http://dx.doi.org/10.1038/ncomms11804

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