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Low birth weight may increase body fat mass in adult women with polycystic ovarian syndrome

BACKGROUND: Women engaged with polycystic ovarian syndrome (PCOS), as the commonest endocrine disorder, are known to have a specific type of adiposity. Birth weight is among different contributors reported to be responsible for this diversity. OBJECTIVE: We aimed to compare the relation between birt...

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Autores principales: Minooee, Sonia, Ramezani Tehrani, Fahimeh, Mirmiran, Parvin, Azizi, Fereidoun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research and Clinical Center for Infertility 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910034/
https://www.ncbi.nlm.nih.gov/pubmed/27326419
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author Minooee, Sonia
Ramezani Tehrani, Fahimeh
Mirmiran, Parvin
Azizi, Fereidoun
author_facet Minooee, Sonia
Ramezani Tehrani, Fahimeh
Mirmiran, Parvin
Azizi, Fereidoun
author_sort Minooee, Sonia
collection PubMed
description BACKGROUND: Women engaged with polycystic ovarian syndrome (PCOS), as the commonest endocrine disorder, are known to have a specific type of adiposity. Birth weight is among different contributors reported to be responsible for this diversity. OBJECTIVE: We aimed to compare the relation between birth weight and body fat mass (BFM)/ body lean mass (BLM) in PCOS and their age and body mass index (BMI) matched normal controls. MATERIALS AND METHODS: In this case-control study, a total number of 70 reproductive aged women, diagnosed with PCOS and 70 age- BMI matched healthy women without hirsutism and/or ovulatory dysfunction were recruited., control group had no polycystic ovaries in ultrasonographic scans. A detailed history of birth weight was taken and was divided into the following categories: <2,500 (low birth weight, LBW) and 2,500-4,000 (normal birth weight; NBW). RESULTS: Results showed that LBW prevalence was higher in women with PCOS than in controls (19.3% (27) vs. 15.7% (22)). Also body fat and lean mass (BFM, BLM) have increased in adult women with PCOS who were born underweight compared to their normal (19.8±9.05 vs. 12.9±4.5, p=0.001 and 48.9±6.9 vs. 43.2±5.8, p=0.004 respectively). CONCLUSION: Fetal birth weight influences on the adulthood obesity, BFM and BLM. This impact is different among women with and without PCOS.
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spelling pubmed-49100342016-06-20 Low birth weight may increase body fat mass in adult women with polycystic ovarian syndrome Minooee, Sonia Ramezani Tehrani, Fahimeh Mirmiran, Parvin Azizi, Fereidoun Int J Reprod Biomed Original Article BACKGROUND: Women engaged with polycystic ovarian syndrome (PCOS), as the commonest endocrine disorder, are known to have a specific type of adiposity. Birth weight is among different contributors reported to be responsible for this diversity. OBJECTIVE: We aimed to compare the relation between birth weight and body fat mass (BFM)/ body lean mass (BLM) in PCOS and their age and body mass index (BMI) matched normal controls. MATERIALS AND METHODS: In this case-control study, a total number of 70 reproductive aged women, diagnosed with PCOS and 70 age- BMI matched healthy women without hirsutism and/or ovulatory dysfunction were recruited., control group had no polycystic ovaries in ultrasonographic scans. A detailed history of birth weight was taken and was divided into the following categories: <2,500 (low birth weight, LBW) and 2,500-4,000 (normal birth weight; NBW). RESULTS: Results showed that LBW prevalence was higher in women with PCOS than in controls (19.3% (27) vs. 15.7% (22)). Also body fat and lean mass (BFM, BLM) have increased in adult women with PCOS who were born underweight compared to their normal (19.8±9.05 vs. 12.9±4.5, p=0.001 and 48.9±6.9 vs. 43.2±5.8, p=0.004 respectively). CONCLUSION: Fetal birth weight influences on the adulthood obesity, BFM and BLM. This impact is different among women with and without PCOS. Research and Clinical Center for Infertility 2016-05 /pmc/articles/PMC4910034/ /pubmed/27326419 Text en http://creativecommons.org/licenses/by/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Minooee, Sonia
Ramezani Tehrani, Fahimeh
Mirmiran, Parvin
Azizi, Fereidoun
Low birth weight may increase body fat mass in adult women with polycystic ovarian syndrome
title Low birth weight may increase body fat mass in adult women with polycystic ovarian syndrome
title_full Low birth weight may increase body fat mass in adult women with polycystic ovarian syndrome
title_fullStr Low birth weight may increase body fat mass in adult women with polycystic ovarian syndrome
title_full_unstemmed Low birth weight may increase body fat mass in adult women with polycystic ovarian syndrome
title_short Low birth weight may increase body fat mass in adult women with polycystic ovarian syndrome
title_sort low birth weight may increase body fat mass in adult women with polycystic ovarian syndrome
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910034/
https://www.ncbi.nlm.nih.gov/pubmed/27326419
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