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Mammalian Target of Rapamycin: Its Role in Early Neural Development and in Adult and Aged Brain Function
The kinase mammalian target of rapamycin (mTOR) integrates signals triggered by energy, stress, oxygen levels, and growth factors. It regulates ribosome biogenesis, mRNA translation, nutrient metabolism, and autophagy. mTOR participates in various functions of the brain, such as synaptic plasticity,...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910040/ https://www.ncbi.nlm.nih.gov/pubmed/27378854 http://dx.doi.org/10.3389/fncel.2016.00157 |