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58-F, a flavanone from Ophiopogon japonicus, prevents hepatocyte death by decreasing lysosomal membrane permeability
Lysosome membrane permeabilization (LMP) has been implicated in cell death. In the present study, we investigated the relationship between cell death and H(2)O(2)-/CCl(4)-induced LMP in hepatocytes in vitro and following acute liver injury in vivo. The key finding was that H(2)O(2) triggered LMP by...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910050/ https://www.ncbi.nlm.nih.gov/pubmed/27306715 http://dx.doi.org/10.1038/srep27875 |