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Endomembrane-associated RSD-3 is important for RNAi induced by extracellular silencing RNA in both somatic and germ cells of Caenorhabditis elegans
RNA silencing signals in C. elegans spread among cells, leading to RNAi throughout the body. During systemic spread of RNAi, membrane trafficking is thought to play important roles. Here, we show that RNAi Spreading Defective-3 (rsd-3), which encodes a homolog of epsinR, a conserved ENTH (epsin N-te...
Autores principales: | Imae, Rieko, Dejima, Katsufumi, Kage-Nakadai, Eriko, Arai, Hiroyuki, Mitani, Shohei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910058/ https://www.ncbi.nlm.nih.gov/pubmed/27306325 http://dx.doi.org/10.1038/srep28198 |
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