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Endomembrane-associated RSD-3 is important for RNAi induced by extracellular silencing RNA in both somatic and germ cells of Caenorhabditis elegans

RNA silencing signals in C. elegans spread among cells, leading to RNAi throughout the body. During systemic spread of RNAi, membrane trafficking is thought to play important roles. Here, we show that RNAi Spreading Defective-3 (rsd-3), which encodes a homolog of epsinR, a conserved ENTH (epsin N-te...

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Detalles Bibliográficos
Autores principales: Imae, Rieko, Dejima, Katsufumi, Kage-Nakadai, Eriko, Arai, Hiroyuki, Mitani, Shohei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910058/
https://www.ncbi.nlm.nih.gov/pubmed/27306325
http://dx.doi.org/10.1038/srep28198

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