A randomized, double-blind, placebo controlled safety, tolerability, and pharmacokinetic dose escalation study of a gentamicin vancomycin gel in patients undergoing colorectal surgery

BACKGROUND: Despite numerous interventions promulgated by the Surgical Care Improve Project (SCIP) and other organizations, surgical site infection (SSI) continues to be a significant medical problem. DFA-02 is a novel bioresorbable modified-release gel consisting of both gentamicin (16.8 mg/mL) and...

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Detalles Bibliográficos
Autores principales: Bennett-Guerrero, Elliott, Minkowitz, Harold S., Segura-Vasi, Alvaro M., Marcet, Jorge E., White, Jennifer A., Corey, G Ralph, Allenby, Kent S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910209/
https://www.ncbi.nlm.nih.gov/pubmed/27313846
http://dx.doi.org/10.1186/s13741-016-0043-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910209/
https://www.ncbi.nlm.nih.gov/pubmed/27313846
http://dx.doi.org/10.1186/s13741-016-0043-2

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