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OncodriveFML: a general framework to identify coding and non-coding regions with cancer driver mutations
Distinguishing the driver mutations from somatic mutations in a tumor genome is one of the major challenges of cancer research. This challenge is more acute and far from solved for non-coding mutations. Here we present OncodriveFML, a method designed to analyze the pattern of somatic mutations acros...
Autores principales: | Mularoni, Loris, Sabarinathan, Radhakrishnan, Deu-Pons, Jordi, Gonzalez-Perez, Abel, López-Bigas, Núria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910259/ https://www.ncbi.nlm.nih.gov/pubmed/27311963 http://dx.doi.org/10.1186/s13059-016-0994-0 |
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