A review of clinical trial designs used to detect a disease-modifying effect of drug therapy in Alzheimer’s disease and Parkinson’s disease

BACKGROUND: Disease-modification clinical trials in neurodegenerative disorders have struggled to separate symptomatic effects of putative agents from disease-modification. In response, a variety of clinical trial designs have been developed. A systematic review was undertaken to examine which trial...

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Detalles Bibliográficos
Autores principales: McGhee, David J. M., Ritchie, Craig W., Zajicek, John P., Counsell, Carl E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910262/
https://www.ncbi.nlm.nih.gov/pubmed/27312378
http://dx.doi.org/10.1186/s12883-016-0606-3

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