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Crystal structure of a bioactive sesquiterpene isolated from Artemisia reticulata
The title compound, C(15)H(24)O(2) {systematic name: 1-[6-hydroxy-7-(propan-2-yl)-4-methylidene-2,3,3a,4,5,6,7,7a-octahydro-1H-inden-1-yl]ethanone} was isolated from A. reticulata by column chromatography over silica gel by gradient solvent elution. The molecule comprises a bicyclo[4.3.0]non...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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International Union of Crystallography
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910329/ https://www.ncbi.nlm.nih.gov/pubmed/27375864 http://dx.doi.org/10.1107/S2056989016003236 |
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author | Bauri, A. K. Foro, Sabine Do, Nhu Quynh Nguyen |
author_facet | Bauri, A. K. Foro, Sabine Do, Nhu Quynh Nguyen |
author_sort | Bauri, A. K. |
collection | PubMed |
description | The title compound, C(15)H(24)O(2) {systematic name: 1-[6-hydroxy-7-(propan-2-yl)-4-methylidene-2,3,3a,4,5,6,7,7a-octahydro-1H-inden-1-yl]ethanone} was isolated from A. reticulata by column chromatography over silica gel by gradient solvent elution. The molecule comprises a bicyclo[4.3.0]nonane ring bearing acetoxy, hydroxy and isopropyl substituents, and an exocyclic double bond on the cyclohexane ring. In the bicyclic skeleton, the cyclohexane ring adopts a chair conformation ring and the cyclopentane ring is in an envelope conformation. In the crystal, molecules are linked by O—H⋯O hydrogen bonds, forming chains along [010]. These chains are cross-linked by C—H⋯O hydrogen bonds. |
format | Online Article Text |
id | pubmed-4910329 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-49103292016-07-01 Crystal structure of a bioactive sesquiterpene isolated from Artemisia reticulata Bauri, A. K. Foro, Sabine Do, Nhu Quynh Nguyen Acta Crystallogr E Crystallogr Commun Research Communications The title compound, C(15)H(24)O(2) {systematic name: 1-[6-hydroxy-7-(propan-2-yl)-4-methylidene-2,3,3a,4,5,6,7,7a-octahydro-1H-inden-1-yl]ethanone} was isolated from A. reticulata by column chromatography over silica gel by gradient solvent elution. The molecule comprises a bicyclo[4.3.0]nonane ring bearing acetoxy, hydroxy and isopropyl substituents, and an exocyclic double bond on the cyclohexane ring. In the bicyclic skeleton, the cyclohexane ring adopts a chair conformation ring and the cyclopentane ring is in an envelope conformation. In the crystal, molecules are linked by O—H⋯O hydrogen bonds, forming chains along [010]. These chains are cross-linked by C—H⋯O hydrogen bonds. International Union of Crystallography 2016-03-04 /pmc/articles/PMC4910329/ /pubmed/27375864 http://dx.doi.org/10.1107/S2056989016003236 Text en © Bauri et al. 2016 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Research Communications Bauri, A. K. Foro, Sabine Do, Nhu Quynh Nguyen Crystal structure of a bioactive sesquiterpene isolated from Artemisia reticulata |
title | Crystal structure of a bioactive sesquiterpene isolated from Artemisia reticulata
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title_full | Crystal structure of a bioactive sesquiterpene isolated from Artemisia reticulata
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title_fullStr | Crystal structure of a bioactive sesquiterpene isolated from Artemisia reticulata
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title_full_unstemmed | Crystal structure of a bioactive sesquiterpene isolated from Artemisia reticulata
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title_short | Crystal structure of a bioactive sesquiterpene isolated from Artemisia reticulata
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title_sort | crystal structure of a bioactive sesquiterpene isolated from artemisia reticulata |
topic | Research Communications |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910329/ https://www.ncbi.nlm.nih.gov/pubmed/27375864 http://dx.doi.org/10.1107/S2056989016003236 |
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