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Crystal structure of 3-(4-hy­droxy­phen­yl)-2-[(E)-2-phenyl­ethen­yl]quinazolin-4(3H)-one

The title compound, C(22)H(16)N(2)O(2) {systematic name: 3-(4-hy­droxy­phen­yl)-2-[(E)-2-phenyl­ethen­yl]quinazolin-4(3H)-one}, consists of a substituted 2-[(E)-2-aryl­ethen­yl]-3-aryl­quinazolin-4(3H)-one skeleton. The substituents at the ethyl­ene fragment are located in trans positions. The pheny...

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Detalles Bibliográficos
Autores principales: Mierina, Inese, Stepanovs, Dmitrijs, Kuginyte, Jolita, Janichev, Artur, Jure, Mara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910336/
https://www.ncbi.nlm.nih.gov/pubmed/27375880
http://dx.doi.org/10.1107/S2056989016004473
Descripción
Sumario:The title compound, C(22)H(16)N(2)O(2) {systematic name: 3-(4-hy­droxy­phen­yl)-2-[(E)-2-phenyl­ethen­yl]quinazolin-4(3H)-one}, consists of a substituted 2-[(E)-2-aryl­ethen­yl]-3-aryl­quinazolin-4(3H)-one skeleton. The substituents at the ethyl­ene fragment are located in trans positions. The phenyl ring is inclined to the quinazolone ring by 26.44 (19)°, while the 4-hy­droxy­phenyl ring is inclined to the quinazolone ring by 81.25 (8)°. The phenyl ring and the 4-hy­droxy­phenyl ring are inclined to one another by 78.28 (2)°. In the crystal, mol­ecules are connected via O—H⋯O hydrogen bonds, forming a helix along the a-axis direction. The helices are linked by C—H⋯π inter­actions, forming slabs parallel to (001).