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Crystal structure of 3-(4-hydroxyphenyl)-2-[(E)-2-phenylethenyl]quinazolin-4(3H)-one
The title compound, C(22)H(16)N(2)O(2) {systematic name: 3-(4-hydroxyphenyl)-2-[(E)-2-phenylethenyl]quinazolin-4(3H)-one}, consists of a substituted 2-[(E)-2-arylethenyl]-3-arylquinazolin-4(3H)-one skeleton. The substituents at the ethylene fragment are located in trans positions. The pheny...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910336/ https://www.ncbi.nlm.nih.gov/pubmed/27375880 http://dx.doi.org/10.1107/S2056989016004473 |
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author | Mierina, Inese Stepanovs, Dmitrijs Kuginyte, Jolita Janichev, Artur Jure, Mara |
author_facet | Mierina, Inese Stepanovs, Dmitrijs Kuginyte, Jolita Janichev, Artur Jure, Mara |
author_sort | Mierina, Inese |
collection | PubMed |
description | The title compound, C(22)H(16)N(2)O(2) {systematic name: 3-(4-hydroxyphenyl)-2-[(E)-2-phenylethenyl]quinazolin-4(3H)-one}, consists of a substituted 2-[(E)-2-arylethenyl]-3-arylquinazolin-4(3H)-one skeleton. The substituents at the ethylene fragment are located in trans positions. The phenyl ring is inclined to the quinazolone ring by 26.44 (19)°, while the 4-hydroxyphenyl ring is inclined to the quinazolone ring by 81.25 (8)°. The phenyl ring and the 4-hydroxyphenyl ring are inclined to one another by 78.28 (2)°. In the crystal, molecules are connected via O—H⋯O hydrogen bonds, forming a helix along the a-axis direction. The helices are linked by C—H⋯π interactions, forming slabs parallel to (001). |
format | Online Article Text |
id | pubmed-4910336 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-49103362016-07-01 Crystal structure of 3-(4-hydroxyphenyl)-2-[(E)-2-phenylethenyl]quinazolin-4(3H)-one Mierina, Inese Stepanovs, Dmitrijs Kuginyte, Jolita Janichev, Artur Jure, Mara Acta Crystallogr E Crystallogr Commun Research Communications The title compound, C(22)H(16)N(2)O(2) {systematic name: 3-(4-hydroxyphenyl)-2-[(E)-2-phenylethenyl]quinazolin-4(3H)-one}, consists of a substituted 2-[(E)-2-arylethenyl]-3-arylquinazolin-4(3H)-one skeleton. The substituents at the ethylene fragment are located in trans positions. The phenyl ring is inclined to the quinazolone ring by 26.44 (19)°, while the 4-hydroxyphenyl ring is inclined to the quinazolone ring by 81.25 (8)°. The phenyl ring and the 4-hydroxyphenyl ring are inclined to one another by 78.28 (2)°. In the crystal, molecules are connected via O—H⋯O hydrogen bonds, forming a helix along the a-axis direction. The helices are linked by C—H⋯π interactions, forming slabs parallel to (001). International Union of Crystallography 2016-03-22 /pmc/articles/PMC4910336/ /pubmed/27375880 http://dx.doi.org/10.1107/S2056989016004473 Text en © Mierina et al. 2016 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Research Communications Mierina, Inese Stepanovs, Dmitrijs Kuginyte, Jolita Janichev, Artur Jure, Mara Crystal structure of 3-(4-hydroxyphenyl)-2-[(E)-2-phenylethenyl]quinazolin-4(3H)-one |
title | Crystal structure of 3-(4-hydroxyphenyl)-2-[(E)-2-phenylethenyl]quinazolin-4(3H)-one |
title_full | Crystal structure of 3-(4-hydroxyphenyl)-2-[(E)-2-phenylethenyl]quinazolin-4(3H)-one |
title_fullStr | Crystal structure of 3-(4-hydroxyphenyl)-2-[(E)-2-phenylethenyl]quinazolin-4(3H)-one |
title_full_unstemmed | Crystal structure of 3-(4-hydroxyphenyl)-2-[(E)-2-phenylethenyl]quinazolin-4(3H)-one |
title_short | Crystal structure of 3-(4-hydroxyphenyl)-2-[(E)-2-phenylethenyl]quinazolin-4(3H)-one |
title_sort | crystal structure of 3-(4-hydroxyphenyl)-2-[(e)-2-phenylethenyl]quinazolin-4(3h)-one |
topic | Research Communications |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910336/ https://www.ncbi.nlm.nih.gov/pubmed/27375880 http://dx.doi.org/10.1107/S2056989016004473 |
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