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Crystal structure of 3-(4-hy­droxy­phen­yl)-2-[(E)-2-phenyl­ethen­yl]quinazolin-4(3H)-one

The title compound, C(22)H(16)N(2)O(2) {systematic name: 3-(4-hy­droxy­phen­yl)-2-[(E)-2-phenyl­ethen­yl]quinazolin-4(3H)-one}, consists of a substituted 2-[(E)-2-aryl­ethen­yl]-3-aryl­quinazolin-4(3H)-one skeleton. The substituents at the ethyl­ene fragment are located in trans positions. The pheny...

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Autores principales: Mierina, Inese, Stepanovs, Dmitrijs, Kuginyte, Jolita, Janichev, Artur, Jure, Mara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910336/
https://www.ncbi.nlm.nih.gov/pubmed/27375880
http://dx.doi.org/10.1107/S2056989016004473
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author Mierina, Inese
Stepanovs, Dmitrijs
Kuginyte, Jolita
Janichev, Artur
Jure, Mara
author_facet Mierina, Inese
Stepanovs, Dmitrijs
Kuginyte, Jolita
Janichev, Artur
Jure, Mara
author_sort Mierina, Inese
collection PubMed
description The title compound, C(22)H(16)N(2)O(2) {systematic name: 3-(4-hy­droxy­phen­yl)-2-[(E)-2-phenyl­ethen­yl]quinazolin-4(3H)-one}, consists of a substituted 2-[(E)-2-aryl­ethen­yl]-3-aryl­quinazolin-4(3H)-one skeleton. The substituents at the ethyl­ene fragment are located in trans positions. The phenyl ring is inclined to the quinazolone ring by 26.44 (19)°, while the 4-hy­droxy­phenyl ring is inclined to the quinazolone ring by 81.25 (8)°. The phenyl ring and the 4-hy­droxy­phenyl ring are inclined to one another by 78.28 (2)°. In the crystal, mol­ecules are connected via O—H⋯O hydrogen bonds, forming a helix along the a-axis direction. The helices are linked by C—H⋯π inter­actions, forming slabs parallel to (001).
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spelling pubmed-49103362016-07-01 Crystal structure of 3-(4-hy­droxy­phen­yl)-2-[(E)-2-phenyl­ethen­yl]quinazolin-4(3H)-one Mierina, Inese Stepanovs, Dmitrijs Kuginyte, Jolita Janichev, Artur Jure, Mara Acta Crystallogr E Crystallogr Commun Research Communications The title compound, C(22)H(16)N(2)O(2) {systematic name: 3-(4-hy­droxy­phen­yl)-2-[(E)-2-phenyl­ethen­yl]quinazolin-4(3H)-one}, consists of a substituted 2-[(E)-2-aryl­ethen­yl]-3-aryl­quinazolin-4(3H)-one skeleton. The substituents at the ethyl­ene fragment are located in trans positions. The phenyl ring is inclined to the quinazolone ring by 26.44 (19)°, while the 4-hy­droxy­phenyl ring is inclined to the quinazolone ring by 81.25 (8)°. The phenyl ring and the 4-hy­droxy­phenyl ring are inclined to one another by 78.28 (2)°. In the crystal, mol­ecules are connected via O—H⋯O hydrogen bonds, forming a helix along the a-axis direction. The helices are linked by C—H⋯π inter­actions, forming slabs parallel to (001). International Union of Crystallography 2016-03-22 /pmc/articles/PMC4910336/ /pubmed/27375880 http://dx.doi.org/10.1107/S2056989016004473 Text en © Mierina et al. 2016 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Research Communications
Mierina, Inese
Stepanovs, Dmitrijs
Kuginyte, Jolita
Janichev, Artur
Jure, Mara
Crystal structure of 3-(4-hy­droxy­phen­yl)-2-[(E)-2-phenyl­ethen­yl]quinazolin-4(3H)-one
title Crystal structure of 3-(4-hy­droxy­phen­yl)-2-[(E)-2-phenyl­ethen­yl]quinazolin-4(3H)-one
title_full Crystal structure of 3-(4-hy­droxy­phen­yl)-2-[(E)-2-phenyl­ethen­yl]quinazolin-4(3H)-one
title_fullStr Crystal structure of 3-(4-hy­droxy­phen­yl)-2-[(E)-2-phenyl­ethen­yl]quinazolin-4(3H)-one
title_full_unstemmed Crystal structure of 3-(4-hy­droxy­phen­yl)-2-[(E)-2-phenyl­ethen­yl]quinazolin-4(3H)-one
title_short Crystal structure of 3-(4-hy­droxy­phen­yl)-2-[(E)-2-phenyl­ethen­yl]quinazolin-4(3H)-one
title_sort crystal structure of 3-(4-hy­droxy­phen­yl)-2-[(e)-2-phenyl­ethen­yl]quinazolin-4(3h)-one
topic Research Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910336/
https://www.ncbi.nlm.nih.gov/pubmed/27375880
http://dx.doi.org/10.1107/S2056989016004473
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