Epithelium-specific Ets transcription factor-1 acts as a negative regulator of cyclooxygenase-2 in human rheumatoid arthritis synovial fibroblasts

BACKGROUND: Rheumatoid arthritis (RA) is characterized by excessive synovial inflammation. Cyclooxygenase-2 (COX-2) is an enzyme that catalyzes the conversion of arachidonic acid (AA) into prostaglandins. Epithelium-specific Ets transcription factor-1 (ESE-1) was previously demonstrated to upregulat...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Chan-Mi, Gupta, Sahil, Wang, Jiafeng, Johnson, Elizabeth M., Crofford, Leslie J., Marshall, John C., Kapoor, Mohit, Hu, Jim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910355/
https://www.ncbi.nlm.nih.gov/pubmed/27313839
http://dx.doi.org/10.1186/s13578-016-0105-7

Ejemplares similares

Ejemplares similares