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Possible Mechanism of Therapeutic Effect of 3-Methyl-1-phenyl-2-pyrazolin-5-one and Bone Marrow Stromal Cells Combination Treatment in Rat Ischemic Stroke Model

BACKGROUND: The functional improvement following bone marrow stromal cells (BMSCs) transplantation after stroke is directly related to the number of engrafted cells and neurogenesis in the injured brain. Here, we tried to evaluate whether 3-methyl-1-phenyl-2-pyrazolin-5-one (MCI-186), a free radical...

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Detalles Bibliográficos
Autores principales: Shen, Li-Hua, Chen, Jin, Shen, Hua-Chao, Ye, Min, Liu, Xiao-Fei, Ding, Wen-Sen, Sheng, Ya-Feng, Ding, Xin-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910373/
https://www.ncbi.nlm.nih.gov/pubmed/27270545
http://dx.doi.org/10.4103/0366-6999.183418