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A novel approach of longitudinal adverse event evaluation in oncology clinical trials: the Toxicity over Time (ToxT) analysis of clinical trials N9741 and 979254 (Alliance)

BACKGROUND: Traditional methods of reporting adverse events (AEs) in clinical trials are inadequate for modern oncology therapies with chronic administration. Conventional analysis and display of maximum grade AEs do not capture toxicity profiles that evolve over time or longer lasting, lower grade...

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Detalles Bibliográficos
Autores principales: Thanarajasingam, Gita, Atherton, Pamela J., Novotny, Paul J., Loprinzi, Charles L., Sloan, Jeff A., Grothey, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910515/
https://www.ncbi.nlm.nih.gov/pubmed/27083333
http://dx.doi.org/10.1016/S1470-2045(16)00038-3

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