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BRCA1 and BRCA2 rearrangements in Brazilian individuals with Hereditary Breast and Ovarian Cancer Syndrome

Approximately 5-10% of breast cancers are caused by germline mutations in high penetrance predisposition genes. Among these, BRCA1 and BRCA2, which are associated with the Hereditary Breast and Ovarian Cancer (HBOC) syndrome, are the most frequently affected genes. Recent studies confirm that gene r...

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Detalles Bibliográficos
Autores principales:	Ewald, Ingrid Petroni, Cossio, Silvia Liliana, Palmero, Edenir Inez, Pinheiro, Manuela, Nascimento, Ivana Lucia de Oliveira, Machado, Taisa Manuela Bonfim, Sandes, Kiyoko Abe, Toralles, Betânia, Garicochea, Bernardo, Izetti, Patricia, Pereira, Maria Luiza Saraiva, Bock, Hugo, Vargas, Fernando Regla, Moreira, Miguel Ângelo Martins, Peixoto, Ana, Teixeira, Manuel R., Ashton-Prolla, Patricia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Sociedade Brasileira de Genética 2016
Materias:	Special Oncogenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910561/ https://www.ncbi.nlm.nih.gov/pubmed/27303907 http://dx.doi.org/10.1590/1678-4685-GMB-2014-0350

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