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P53 Is Involved in a Three-Dimensional Architecture-Mediated Decrease in Chemosensitivity in Colon Cancer

Three-dimensional (3D) culture models represent a better approximation of solid tumor tissue architecture, especially cell adhesion, in vivo than two-dimensional (2D) cultures do. Here, we explored the role of architecture in chemosensitivity to platinum in colon cancer. Under the 3D culture conditi...

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Detalles Bibliográficos
Autores principales:	He, Jianming, Liang, Xi, Luo, Fen, Chen, Xuedan, Xu, Xueqing, Wang, Fengchao, Zhang, Zhenping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910581/ https://www.ncbi.nlm.nih.gov/pubmed/27313779 http://dx.doi.org/10.7150/jca.14506

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