Long Noncoding RNA: Recent Updates in Atherosclerosis

Long noncoding RNAs belong to a class of noncoding RNAs longer than 200 nucleotides with the epigenetic regulation potential. As a novel molecular regulator, lncRNAs are often dysregulated in various pathological conditions and display multiple functions in a wide range of biological processes. Give...

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Detalles Bibliográficos
Autores principales: Li, Hao, Zhu, Hongming, Ge, Junbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910607/
https://www.ncbi.nlm.nih.gov/pubmed/27314829
http://dx.doi.org/10.7150/ijbs.14430
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author Li, Hao
Zhu, Hongming
Ge, Junbo
author_facet Li, Hao
Zhu, Hongming
Ge, Junbo
author_sort Li, Hao
collection PubMed
description Long noncoding RNAs belong to a class of noncoding RNAs longer than 200 nucleotides with the epigenetic regulation potential. As a novel molecular regulator, lncRNAs are often dysregulated in various pathological conditions and display multiple functions in a wide range of biological processes. Given that recent studies have indicated that lncRNAs are involved in atherosclerosis-related smooth muscle cell, endothelial cell, macrophage and lipid metabolism regulation, it is pertinent to understand the potential function of lncRNAs in atherosclerosis development. This review will highlight the recent updates of lncRNAs in atherogenesis and also discuss their potential roles as novel therapeutic targets.
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spelling pubmed-49106072016-06-16 Long Noncoding RNA: Recent Updates in Atherosclerosis Li, Hao Zhu, Hongming Ge, Junbo Int J Biol Sci Research Paper Long noncoding RNAs belong to a class of noncoding RNAs longer than 200 nucleotides with the epigenetic regulation potential. As a novel molecular regulator, lncRNAs are often dysregulated in various pathological conditions and display multiple functions in a wide range of biological processes. Given that recent studies have indicated that lncRNAs are involved in atherosclerosis-related smooth muscle cell, endothelial cell, macrophage and lipid metabolism regulation, it is pertinent to understand the potential function of lncRNAs in atherosclerosis development. This review will highlight the recent updates of lncRNAs in atherogenesis and also discuss their potential roles as novel therapeutic targets. Ivyspring International Publisher 2016-06-07 /pmc/articles/PMC4910607/ /pubmed/27314829 http://dx.doi.org/10.7150/ijbs.14430 Text en © Ivyspring International Publisher. Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited. See http://ivyspring.com/terms for terms and conditions.
spellingShingle Research Paper
Li, Hao
Zhu, Hongming
Ge, Junbo
Long Noncoding RNA: Recent Updates in Atherosclerosis
title Long Noncoding RNA: Recent Updates in Atherosclerosis
title_full Long Noncoding RNA: Recent Updates in Atherosclerosis
title_fullStr Long Noncoding RNA: Recent Updates in Atherosclerosis
title_full_unstemmed Long Noncoding RNA: Recent Updates in Atherosclerosis
title_short Long Noncoding RNA: Recent Updates in Atherosclerosis
title_sort long noncoding rna: recent updates in atherosclerosis
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910607/
https://www.ncbi.nlm.nih.gov/pubmed/27314829
http://dx.doi.org/10.7150/ijbs.14430
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