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Challenges in translating endpoints from trials to observational cohort studies in oncology

Clinical trials are considered the gold standard for examining drug efficacy and for approval of new drugs. Medical databases and population surveillance registries are valuable resources for post-approval observational research, which are increasingly used in studies of benefits and risk of new can...

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Detalles Bibliográficos
Autores principales: Ording, Anne Gulbech, Cronin-Fenton, Deirdre, Ehrenstein, Vera, Lash, Timothy L, Acquavella, John, Rørth, Mikael, Sørensen, Henrik Toft
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910679/
https://www.ncbi.nlm.nih.gov/pubmed/27354827
http://dx.doi.org/10.2147/CLEP.S97874