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Reducing prostaglandin E(2) production to raise cancer immunogenicity

Cyclooxygenases (COX), commonly upregulated in numerous cancers, generate prostaglandin E(2) (PGE(2)), which has been implicated in key aspects of malignant growth including proliferation, invasion and angiogenesis. Recently, we showed that production of PGE(2) by cancer cells dominantly enables pro...

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Detalles Bibliográficos
Autores principales: Zelenay, Santiago, Reis e Sousa, Caetano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910741/
https://www.ncbi.nlm.nih.gov/pubmed/27467936
http://dx.doi.org/10.1080/2162402X.2015.1123370