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Reducing prostaglandin E(2) production to raise cancer immunogenicity
Cyclooxygenases (COX), commonly upregulated in numerous cancers, generate prostaglandin E(2) (PGE(2)), which has been implicated in key aspects of malignant growth including proliferation, invasion and angiogenesis. Recently, we showed that production of PGE(2) by cancer cells dominantly enables pro...
Autores principales: | Zelenay, Santiago, Reis e Sousa, Caetano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910741/ https://www.ncbi.nlm.nih.gov/pubmed/27467936 http://dx.doi.org/10.1080/2162402X.2015.1123370 |
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