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Toll-like receptor (TLR4) Asp299Gly and Thr399Ile polymorphisms in relation to clinical falciparum malaria among Nigerian children: a multisite cross-sectional immunogenetic study in Lagos

INTRODUCTION: This study determined the association of TLR4 Asp299Gly and Thr399Ile with uncomplicated and severe malaria among Nigerian children of similar ethnic background in Lagos. The association of these SNPs with high parasite density, malnutrition, hyperpyrexia and anaemia was also investiga...

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Detalles Bibliográficos
Autores principales: Iwalokun, Bamidele Abiodun, Oluwadun, Afolabi, Iwalokun, Senapon Olusola, Agomo, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910769/
https://www.ncbi.nlm.nih.gov/pubmed/27350800
http://dx.doi.org/10.1186/s41021-015-0002-z