Cargando…

Replication and Relevance of Multiple Susceptibility Loci Discovered from Genome Wide Association Studies for Type 2 Diabetes in an Indian Population

AIM: Several genetic variants for type 2 diabetes (T2D) have been identified through genome wide association studies (GWAS) from Caucasian population; however replication studies were not consistent across various ethnicities. Objective of the current study is to examine the possible correlation of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Phani, Nagaraja M., Adhikari, Prabha, Nagri, Shivashankara K., D’Souza, Sydney C., Satyamoorthy, Kapaettu, Rai, Padmalatha S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911058/ https://www.ncbi.nlm.nih.gov/pubmed/27310578 http://dx.doi.org/10.1371/journal.pone.0157364

Ejemplares similares

Impact of KCNJ11, TCF7L2, SLC30A8, IGF2BP2, PPARG, SLC47A1, STK11, HHEX, KCNQ1, CDKAL1, FTO, CYP2C9, ADIPOQ, CAPN10 gene polymorphisms on risk of type 2 diabetes and therapeutic response to sulfonylurea and metformin therapy
por: Phani, Nagaraja, et al.
Publicado: (2014)

Population Specific Impact of Genetic Variants in KCNJ11 Gene to Type 2 Diabetes: A Case-Control and Meta-Analysis Study
por: Phani, Nagaraja M., et al.
Publicado: (2014)

Effect of licorice on patients with HSD11B1 gene polymorphisms- a pilot study
por: Devang, Nayana, et al.
Publicado: (2021)

Pharmacogenomic considerations for repurposing of dexamethasone as a potential drug against SARS-CoV-2 infection
por: Vohra, Manik, et al.
Publicado: (2021)

Elevated homocysteine levels in type 2 diabetes induce constitutive neutrophil extracellular traps
por: Joshi, Manjunath B, et al.
Publicado: (2016)

Pharmacogenomics deliberations of 2-deoxy-d-glucose in the treatment of COVID-19 disease: an in silico approach
por: Prabhu, Navya B., et al.
Publicado: (2022)

In vitro bioproduction and enhancement of moscatilin from a threatened tropical epiphytic orchid, Dendrobium ovatum (Willd.) Kraenzl
por: Pujari, Ipsita, et al.
Publicado: (2021)

Genetic and epigenetic changes in host ABCB1 influences malaria susceptibility to Plasmodium falciparum
por: Gupta, Himanshu, et al.
Publicado: (2017)

Cytotoxicity and radiosensitizing potency of Moscatilin in cancer cells at low radiation doses of X-ray and UV-C
por: Pujari, Ipsita, et al.
Publicado: (2021)

Distinct metabolic signatures in blood plasma of bisphenol A–exposed women with polycystic ovarian syndrome
por: Prabhu, Navya B., et al.
Publicado: (2023)

An Investigation of Genome-Wide Studies Reported Susceptibility Loci for Ulcerative Colitis Shows Limited Replication in North Indians
por: Juyal, Garima, et al.
Publicado: (2011)

Genetic variation in genes involved in folate and drug metabolism in a south Indian population
por: Rai, Padmalatha S, et al.
Publicado: (2011)

Novel mutation in an Indian patient with Methylmalonic Acidemia, cblA type
por: Girisha, Katta Mohan, et al.
Publicado: (2012)

Genomic loci susceptible to replication errors in cancer cells.
por: Krajinovic, M., et al.
Publicado: (1998)

Prognostic Relevance of Urinary Bladder Cancer Susceptibility Loci
por: Grotenhuis, Anne J., et al.
Publicado: (2014)

MTHFR Gene variants C677T, A1298C and association with Down syndrome: A Case-control study from South India
por: Cyril, Cyrus, et al.
Publicado: (2009)

Development of allele specific hybridization assay and computer aided tool for detection of genetic variations in folate pathway genes
por: Ravishankara, et al.
Publicado: (2014)

Public Health Genomics: the essential part for good governance in public health
por: Brand, Angela, et al.
Publicado: (2016)

Oxidative Stress in Cognitive and Epigenetic Aging: A Retrospective Glance
por: Kandlur, Aditi, et al.
Publicado: (2020)

Replication of Genome Wide Association Studies on Hepatocellular Carcinoma Susceptibility Loci in a Chinese Population
por: Chen, Kangmei, et al.
Publicado: (2013)

Role of IL-6/JAK/STAT pathway in inducing vascular insulin resistance
por: Balakrishnan, Aswath, et al.
Publicado: (2014)

CmirC: an integrated database of clustered miRNAs co-localized with copy number variations in cancer
por: Ware, Akshay Pramod, et al.
Publicado: (2022)

Integrated multiomics analysis of chromosome 19 miRNA cluster in bladder cancer
por: Ware, Akshay Pramod, et al.
Publicado: (2023)

DNA barcoding of authentic and substitute samples of herb of the family Asparagaceae and Asclepiadaceae based on the ITS2 region
por: Rai, Padmalatha S, et al.
Publicado: (2012)

Replication of genome‐wide association study (GWAS) susceptibility loci in a Latino bipolar disorder cohort
por: Gonzalez, Suzanne, et al.
Publicado: (2016)

Genome-Wide Association Studies (GWAS) breast cancer susceptibility loci in Arabs: susceptibility and prognostic implications in Tunisians
por: Shan, Jingxuan, et al.
Publicado: (2012)

Prakriti phenotypes as a stratifier of gut microbiome: A new frontier in personalized medicine?
por: Jnana, Apoorva, et al.
Publicado: (2020)

Advances in development and application of human organoids
por: Shankaran, Abhijith, et al.
Publicado: (2021)

Therapeutics through glycobiology: an approach for targeted elimination of malaria
por: Divya, Mallya, et al.
Publicado: (2023)

Effect of 3-Month Yoga on Oxidative Stress in Type 2 Diabetes With or Without Complications: A controlled clinical trial
por: Hegde, Shreelaxmi V., et al.
Publicado: (2011)

Response to Comment on: Hegde et al. Effect of 3-Month Yoga on Oxidative Stress in Type 2 Diabetes With or Without Complications: A Controlled Clinical Trial. Diabetes Care 2011;34: 2208–2210
por: Hegde, Shreelaxmi V., et al.
Publicado: (2012)

GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer
por: Pharoah, Paul D. P., et al.
Publicado: (2013)

Enhanced meta-analysis and replication studies identify five new psoriasis susceptibility loci
por: Tsoi, Lam C, et al.
Publicado: (2015)

Replication of British Rheumatoid Arthritis Susceptibility Loci in Two Unrelated Chinese Population Groups
por: Li, Hua, et al.
Publicado: (2013)

Replication of Putative Susceptibility Loci from Genome-Wide Association Studies Associated with Coronary Atherosclerosis in Chinese Han Population
por: Xie, Fang, et al.
Publicado: (2011)

Association of serum ferritin with severity and clinical outcome in COVID-19 patients: An observational study in a tertiary healthcare facility
por: Kurian, Shilia Jacob, et al.
Publicado: (2023)

Meta-analysis of genome-wide association studies discovers multiple loci for chronic lymphocytic leukemia
por: Berndt, Sonja I., et al.
Publicado: (2016)

A Bayesian Method for Evaluating and Discovering Disease Loci Associations
por: Jiang, Xia, et al.
Publicado: (2011)

Detection of susceptibility loci by genome-wide linkage analysis
por: Babron, Marie-Claude, et al.
Publicado: (2005)

Replication of Associations of Genetic Loci Outside the HLA Region With Susceptibility to Anti–Cyclic Citrullinated Peptide–Negative Rheumatoid Arthritis
por: Viatte, Sebastien, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_ea239cbv8daatqru1rllvmj9pm