Influenza A Virus Challenge Models in Cynomolgus Macaques Using the Authentic Inhaled Aerosol and Intra-Nasal Routes of Infection

Non-human primates are the animals closest to humans for use in influenza A virus challenge studies, in terms of their phylogenetic relatedness, physiology and immune systems. Previous studies have shown that cynomolgus macaques (Macaca fascicularis) are permissive for infection with H1N1pdm influen...

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Detalles Bibliográficos
Autores principales: Marriott, Anthony C., Dennis, Mike, Kane, Jennifer A., Gooch, Karen E., Hatch, Graham, Sharpe, Sally, Prevosto, Claudia, Leeming, Gail, Zekeng, Elsa-Gayle, Staples, Karl J., Hall, Graham, Ryan, Kathryn A., Bate, Simon, Moyo, Nathifa, Whittaker, Catherine J., Hallis, Bassam, Silman, Nigel J., Lalvani, Ajit, Wilkinson, Tom M., Hiscox, Julian A., Stewart, James P., Carroll, Miles W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911124/
https://www.ncbi.nlm.nih.gov/pubmed/27311020
http://dx.doi.org/10.1371/journal.pone.0157887

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