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Epigenetic silencing of olfactomedin-4 enhances gastric cancer cell invasion via activation of focal adhesion kinase signaling

Downregulation of olfactomedin-4 (OLFM4) is associated with tumor progression, lymph node invasion and metastases. However, whether or not downregulation of OLFM4 is associated with epigenetic silencing remains unknown. In this study, we investigate the role of OLFM4 in gastric cancer cell invasion....

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Detalles Bibliográficos
Autores principales: Guo, Li-Li, He, Zhao-Cai, Yang, Chang-Qing, Qiao, Pei-Tang, Yin, Guo-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911205/
https://www.ncbi.nlm.nih.gov/pubmed/26303970
http://dx.doi.org/10.5483/BMBRep.2015.48.11.130