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TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action

When integral membrane proteins are visualized in detergents or other artificial systems, an important layer of information is lost regarding lipid interactions and their effects on protein structure. This is especially relevant to proteins for which lipids play both structural and regulatory roles....

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Detalles Bibliográficos
Autores principales: Gao, Yuan, Cao, Erhu, Julius, David, Cheng, Yifan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911334/
https://www.ncbi.nlm.nih.gov/pubmed/27281200
http://dx.doi.org/10.1038/nature17964

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