Pharmacologic Inhibition of Host Phosphodiesterase-4 Improves Isoniazid-Mediated Clearance of Mycobacterium tuberculosis

The lengthy duration of multidrug therapy needed to cure tuberculosis (TB) poses significant challenges for global control of the disease. Moreover, chronic inflammation associated with TB leads to pulmonary damage that can remain even after successful cure. Thus, there is a great need for the devel...

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Detalles Bibliográficos
Autores principales: Subbian, Selvakumar, Koo, Mi-Sun, Tsenova, Liana, Khetani, Vikram, Zeldis, Jerome B., Fallows, Dorothy, Kaplan, Gilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911353/
https://www.ncbi.nlm.nih.gov/pubmed/27379099
http://dx.doi.org/10.3389/fimmu.2016.00238

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911353/
https://www.ncbi.nlm.nih.gov/pubmed/27379099
http://dx.doi.org/10.3389/fimmu.2016.00238

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