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Proaggregant nuclear factor(s) trigger rapid formation of α-synuclein aggregates in apoptotic neurons
Cell-to-cell transmission of α-synuclein (αS) aggregates has been proposed to be responsible for progressive αS pathology in Parkinson disease (PD) and related disorders, including dementia with Lewy bodies. In support of this concept, a growing body of in vitro and in vivo experimental evidence sho...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911378/ https://www.ncbi.nlm.nih.gov/pubmed/26839082 http://dx.doi.org/10.1007/s00401-016-1542-4 |