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Transient Expression of WNT2 Promotes Somatic Cell Reprogramming by Inducing β-Catenin Nuclear Accumulation
Treatment with several Wnt/β-catenin signaling pathway regulators can change the cellular reprogramming efficiency; however, the dynamics and role of endogenous Wnt/β-catenin signaling in reprogramming remain largely unanswered. Here we identify the upregulation of WNT2 and subsequent β-catenin nucl...
Autores principales: | Kimura, Mizuki, Nakajima-Koyama, May, Lee, Joonseong, Nishida, Eisuke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911497/ https://www.ncbi.nlm.nih.gov/pubmed/27211212 http://dx.doi.org/10.1016/j.stemcr.2016.04.012 |
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