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Controlled Inhibition of the Mesenchymal Stromal Cell Pro-inflammatory Secretome via Microparticle Engineering

Mesenchymal stromal cells (MSCs) are promising therapeutic candidates given their potent immunomodulatory and anti-inflammatory secretome. However, controlling the MSC secretome post-transplantation is considered a major challenge that hinders their clinical efficacy. To address this, we used a micr...

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Detalles Bibliográficos
Autores principales: Ranganath, Sudhir H., Tong, Zhixiang, Levy, Oren, Martyn, Keir, Karp, Jeffrey M., Inamdar, Maneesha S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911501/
https://www.ncbi.nlm.nih.gov/pubmed/27264972
http://dx.doi.org/10.1016/j.stemcr.2016.05.003