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Myeloid thrombomodulin lectin-like domain inhibits osteoclastogenesis and inflammatory bone loss
Osteoclastogenesis is an essential process during bone metabolism which can also be promoted by inflammatory signals. Thrombomodulin (TM), a transmembrane glycoprotein, exerts anti-inflammatory activities such as neutralization of proinflammatory high-mobility group box 1 (HMGB1) through TM lectin-l...
Autores principales: | Cheng, Tsung-Lin, Lai, Chao-Han, Shieh, Shyh-Jou, Jou, Yin-Bo, Yeh, Jwu-Lai, Yang, Ai-Lun, Wang, Yan-Hsiung, Wang, Chau-Zen, Chen, Chung-Hwan, Shi, Guey-Yueh, Ho, Mei-Ling, Wu, Hua-Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911607/ https://www.ncbi.nlm.nih.gov/pubmed/27311356 http://dx.doi.org/10.1038/srep28340 |
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