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Expression of Polo-Like Kinase 4(PLK4) in Breast Cancer and Its Response to Taxane-Based Neoadjuvant Chemotherapy

Purpose: Polo-like kinase 4(PLK4) is an important evolutionarily regulator involved in centrosome duplication. We here investigated the expression of PLK4 mRNA and PLK4 in breast cancer, and evaluated its predictive value for response to taxane-based neoadjuvant chemotherapy. Method: The PLK4 mRNA e...

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Detalles Bibliográficos
Autores principales: Li, Zhenhua, Dai, Kun, Wang, Chijuan, Song, Yawen, Gu, Feng, Liu, Fangfang, Fu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911880/
https://www.ncbi.nlm.nih.gov/pubmed/27326256
http://dx.doi.org/10.7150/jca.14307