An RNA matchmaker protein regulates the activity of the long noncoding RNA HOTAIR

The human long noncoding RNA (lncRNA) HOTAIR acts in trans to recruit the Polycomb repressive complex 2 (PRC2) to the HOXD gene cluster and to promote gene silencing during development. In breast cancers, overexpression of HOTAIR increases metastatic potential via the repression of many additional g...

Descripción completa

Detalles Bibliográficos
Autores principales: Meredith, Emily K., Balas, Maggie M., Sindy, Karla, Haislop, Krystal, Johnson, Aaron M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911922/
https://www.ncbi.nlm.nih.gov/pubmed/27146324
http://dx.doi.org/10.1261/rna.055830.115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911922/
https://www.ncbi.nlm.nih.gov/pubmed/27146324
http://dx.doi.org/10.1261/rna.055830.115

Ejemplares similares