Virtual microdissection identifies distinct tumor- and stroma-specific subtypes of pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) remains a lethal disease with a 5-year survival of 4%. A key hallmark of PDAC is extensive stromal involvement, which makes capturing precise tumor-specific molecular information difficult. Here, we have overcome this problem by applying blind source separatio...

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Detalles Bibliográficos
Autores principales: Moffitt, Richard A., Marayati, Raoud, Flate, Elizabeth L., Volmar, Keith E., Loeza, S. Gabriela Herrera, Hoadley, Katherine A., Rashid, Naim U., Williams, Lindsay A., Eaton, Samuel C., Chung, Alexander H., Smyla, Jadwiga K., Anderson, Judy M., Kim, Hong Jin, Bentrem, David J., Talamonti, Mark S., Iacobuzio-Donahue, Christine A., Hollingsworth, Michael A., Yeh, Jen Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912058/
https://www.ncbi.nlm.nih.gov/pubmed/26343385
http://dx.doi.org/10.1038/ng.3398

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