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Differential Transcriptome Networks between IDO1-Knockout and Wild-Type Mice in Brain Microglia and Macrophages

Microglia in the brain and macrophages in peripheral organs are cell types responsible for immune response to challenges. Indoleamine 2,3-dioxygenase 1 (IDO1) is an immunomodulatory enzyme of the tryptophan pathway that is expressed in the brain. The higher activity of IDO1 in response to immune cha...

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Detalles Bibliográficos
Autores principales:	Gonzalez-Pena, Dianelys, Nixon, Scott E., Southey, Bruce R., Lawson, Marcus A., McCusker, Robert H., Hernandez, Alvaro G., Dantzer, Robert, Kelley, Keith W., Rodriguez-Zas, Sandra L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912085/ https://www.ncbi.nlm.nih.gov/pubmed/27314674 http://dx.doi.org/10.1371/journal.pone.0157727

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